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Synfacts 2008(5): 0442-0442  
DOI: 10.1055/s-2008-1072698
Synthesis of Natural Products and Potential Drugs
© Georg Thieme Verlag Stuttgart · New York

Synthesis of (+)-Didemniserinolipid B

Contributor(s): Philip Kocienski, Indu Dager
C. C. Marvin, E. A. Voight, S. D. Burke*
University of Wisconsin-Madison, USA
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Publication History

Publication Date:
23 April 2008 (online)

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Significance

Didemniserinolipid B is isolated from the tunicate Didemnum sp. The central bicyclic core is constructed by intermolecular ketalization to give C, followed by intramolecular RCM so that D could be used for the preparation of ana­logues by varying the side chain.