PDF herunterladen
Synfacts 2008(7): 0704-0704  
DOI: 10.1055/s-2008-1077804
Synthesis of Materials and Unnatural Products
© Georg Thieme Verlag Stuttgart · New York

And Click, Instant Monomer

Contributor(s): Timothy M. Swager, Brett VanVeller
K. Takizawa, H. Nulwala, R. J. Thibault, P. Lowenhielm, K. Yoshinaga, K. L. Wooley, C. J. Hawker*
University of California, Santa Barbara, The Dow Chemical Company, Freeport and Washington University in St. Louis, USA; Mitsubishi Chemical Group Science and Technology Research Center, Yokohama and Kyushu Institute of Technology, Fukuoka, Japan
Weitere Informationen

Publikationsverlauf

Publikationsdatum:
20. Juni 2008 (online)

    Lizenzen und Reprints

Significance

The authors demonstrate a variety of convenient syntheses of a new family of monomers based on the 4-vinyl-triazole scaffold. The robust and highly efficient Cu(I)-catalyzed azide/acetylene coupling permits synthesis of a vast ­library of structurally diverse monomers. Further, the above strategy is an improvement over previous syntheses that use the expensive TMS-protected vinylacetylene (J. Am. Chem. Soc. 2006, 128, 12084).