Synfacts 2008(7): 0713-0713  
DOI: 10.1055/s-2008-1077845
Metal-Catalyzed Asymmetric Synthesis and Stereoselective Reactions
© Georg Thieme Verlag Stuttgart · New York

Pd/La Complex for anti-Selective Catalytic Asymmetric Nitroaldol Reactions

Contributor(s): Hisashi Yamamoto, Joshua P. Abell
S. Handa, K. Nagawa, Y. Sohtome, S. Matsunaga*, M. Shibasaki*
The University of Tokyo, Japan
Weitere Informationen

Publikationsverlauf

Publikationsdatum:
20. Juni 2008 (online)

Significance

A limited number of reports describe the anti-selective synthesis of chiral β-amino alcohols. This report describes the design of a simple and efficient catalyst with a broad substrate scope and practical applicability. The authors nicely demonstrate the short syntheses of two β-adrenoceptor agonists.