Synfacts, Table of Contents Synfacts 2025; 21(04): 423DOI: 10.1055/a-2539-3755 Innovative Drug Discovery and Development Scaffold Hopping with IL-17 Antagonists – Exploiting an Oxygen-to-Sulfur Interaction to Favor Planarity Contributor(s): Antonia F. Stepan (Roche) , Nicholas A. Meanwell (Baruch S. Blumberg Inst., U. Michigan, Rutgers. U.) Recommend Article Abstract Buy Article Keywords Keywordsscaffold hopping - oxygen-to-sulfur interaction - conformational bias Full Text