A Protecting Group for Two-Photon Uncaging

S. Gug; F. Bolze; A. Specht; C. Bourgogne; M. Goeldner; J.-F. Nicoud

doi:10.1055/s-0028-1087501

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Synfacts 2009(2): 0155-0155
DOI: 10.1055/s-0028-1087501

Synthesis of Materials and Unnatural Products

A Protecting Group for Two-Photon Uncaging

Contributor(s): Timothy M. Swager, Jan M. Schnorr
S. Gug, F. Bolze*, A. Specht, C. Bourgogne, M. Goeldner, J.-F. Nicoud
Institut Gilbert Laustriat, Illkirch and Institut de Physique et Chimie des Matériaux de Strasbourg, France

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Publication History

Publication Date:
22 January 2009 (online)

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Significance

The authors used a molecular engineering strategy to synthesize a protecting group for two-photon uncaging. The protected glutamate 6 can be released with high efficiency upon excitation with one or two photons.