Synfacts 2009(2): 0199-0199  
DOI: 10.1055/s-0028-1087657
Metal-Mediated Synthesis
© Georg Thieme Verlag Stuttgart ˙ New York

Re-Catalyzed Cycloaddition of β-Keto Esters to Aliphatic Allenes

Contributor(s): Paul Knochel, Tobias Thaler
S. S. Yuda, Y. Kuninobu*, K. Takai*
Okayama University, Japan
Further Information

Publication History

Publication Date:
22 January 2009 (online)

Significance

A novel diastereoselective annulation reaction between β-keto esters and aliphatic allenes is presented. The reaction leads to the formation of stereodefined cyclopentenes, in which three stereogenic centers are controlled, including an all-carbon quaternary center.