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Synfacts 2009(5): 0504-0504  
DOI: 10.1055/s-0029-1216573
Synthesis of Materials and Unnatural Products
© Georg Thieme Verlag Stuttgart ˙ New York

Synthesis of Novel, Helical Spiroannelated Hydrocarbon Rings

Contributor(s): Timothy M. Swager, Mindy Levine
I. Meyer-Wilmes, R. Gerke, L. Fitjer*
Universität Göttingen, Germany
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Publication History

Publication Date:
22 April 2009 (online)

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Significance

The first synthesis of compounds 8 and 12 are reported. These structures represent the first helical hydrocarbons of 1,3-spiroannelated cyclopentane rings that bear no functionalities. While these compounds were synthesized in ­racemic form, enantiomeric resolution of the ­compounds could lead to enantiopure helical compounds with substantial optical rotations.