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Synfacts 2010(8): 0966-0966  
DOI: 10.1055/s-0030-1257788
Polymer-Supported Synthesis
© Georg Thieme Verlag Stuttgart ˙ New York

Microwave-Assisted Synthesis of Fused Quinoxalinones

Contributor(s): Yasuhiro Uozumi, Yoichi M. A. Yamada, Toshihiro Watanabe
J.-J. Lai, D. B. Salunke, C.-M. Sun*
National Chiao Tung University, Hsinchu, Taiwan
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Publication History

Publication Date:
22 July 2010 (online)

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Significance

The synthesis of indole-fused pyrazino-/diazepinoquinoxalinones 8 and 9 via reductive cyclization of PEG-supported intermediates 5 was achieved under microwave irradiation in 63-91% yield (15 examples) and 45-92% yield (15 examples), respectively.