PDF herunterladen
Synfacts 2011(4): 0393-0393  
DOI: 10.1055/s-0030-1259658
Metal-Catalyzed Asymmetric Synthesis and Stereoselective Reactions
© Georg Thieme Verlag Stuttgart ˙ New York

Rhodium(I)-Catalyzed Asymmetric Desymmetrization by Retro-Allylation

Contributor(s): Hisashi Yamamoto, Patrick Brady
M. Waibel, N. Cramer*
ETH Zürich, Switzerland
Weitere Informationen

Publikationsverlauf

Publikationsdatum:
18. März 2011 (online)

    Lizenzen und Reprints

Significance

A rhodium-catalyzed desymmetrization of meso-norbornenols is described, generating cyclic compounds in high yield and enantio­selectivity. Judicious choice of substrate and reaction conditions allows the formation of different products, making this a highly flexible catalytic system.