Cu-Catalyzed Benzylic C-H Oxidation Using Imines
as Directing Groups

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Synfacts 2011(6): 0658-0658
DOI: 10.1055/s-0030-1259898

Metal-Mediated Synthesis

Contributor(s): Paul Knochel, Andreas J. Wagner
L. Zhang, G. Y. Ang, S. Chiba*
Nanyang Technological University, Singapore

Further Information

Publication Date:
19 May 2011 (online)

A copper-catalyzed one-pot benzylic C-H oxygenation under aerobic conditions has been developed starting from aryl nitriles and Grignard reagents.