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Synfacts 2011(6): 0590-0590  
DOI: 10.1055/s-0030-1260369
Synthesis of Natural Products and Potential Drugs
© Georg Thieme Verlag Stuttgart ˙ New York

Enantioselective Synthesis of (+)-Salvileucalin B

Contributor(s): Steven V. Ley, James R. Frost
S. Levin, R. R. Nani, S. E. Reisman*
California Institute of Technology, Pasadena, USA
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Publication History

Publication Date:
19 May 2011 (online)

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Significance

Salvileucalin B was isolated in 2008 from the plant Salvia leucantha by Takeya and co-workers and identified as a potential new medicinal lead. Its unusual norcaradiene core, containing a fully substituted cyclopropane ring, has made it a worthy synthesis target.