Copper-Catalyzed Asymmetric Conjugate Addition of Grignard
Reagents

doi:10.1055/s-0030-1260439

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Synfacts 2011(6): 0642-0642
DOI: 10.1055/s-0030-1260439

Metal-Catalyzed Asymmetric Synthesis and Stereoselective Reactions

Copper-Catalyzed Asymmetric Conjugate Addition of Grignard Reagents

Contributor(s): Hisashi Yamamoto, Jiajing Tan
J. F. Teichert, B. L. Feringa*
University of Groningen, The Netherlands

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Publication History

Publication Date:
19 May 2011 (online)

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Significance

The authors developed an efficient catalyst system for the asymmetric addition of Grignard reagents to inactivated courmarins. The desired products were obtained in good yields and enantioselectivities.