RSS-Feed abonnieren
Bitte kopieren Sie die angezeigte URL und fügen sie dann in Ihren RSS-Reader ein.
https://www.thieme-connect.de/rss/thieme/de/10.1055-s-00000131.xml
Synfacts 2014; 10(1): 0100
DOI: 10.1055/s-0033-1340397
DOI: 10.1055/s-0033-1340397
Polymer-Supported Synthesis
Synthesis of Spirooxindoles Using CuFe2O4 Nanoparticles
Weitere Informationen
Publikationsverlauf
Publikationsdatum:
13. Dezember 2013 (online)
Key words
magnetic nanoparticles - cyclic 1,3-diones - activated acetonitriles - isatins - spirooxindoles
Significance
CuFe2O4 nanoparticles catalyzed the three-component coupling of cyclohexane-1,3-diones, activated acetonitriles and isatins to give the corresponding spirooxindoles (38 examples, 81–97% yield).
#
Comment
In the synthesis of product A, the catalyst was recovered magnetically and reused four times (1st reuse: 90% yield, 2nd reuse: 89% yield, 3rd reuse: 88% yield, 4th reuse: 80% yield).
#
#
