Design and Application of 3-Alkyl-2-vinylindoles in Brønsted Acid Catalyzed Reactions

Guang-Jian Mei; Feng Shi

doi:10.1055/s-0036-1588611

Synlett, Inhaltsverzeichnis

Synlett 2016; 27(18): 2515-2524
DOI: 10.1055/s-0036-1588611

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Design and Application of 3-Alkyl-2-vinylindoles in Brønsted Acid Catalyzed Reactions

Guang-Jian Mei

Jiangsu Key Laboratory of Green Synthetic for Functional Materials, School of Chemistry and Chemical Engineering, Jiangsu Normal University, Xuzhou, 221116, P. R. of China eMail: fshi@jsnu.edu.cn

,

Feng Shi*

Jiangsu Key Laboratory of Green Synthetic for Functional Materials, School of Chemistry and Chemical Engineering, Jiangsu Normal University, Xuzhou, 221116, P. R. of China eMail: fshi@jsnu.edu.cn

› Institutsangaben

Abstract

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Abstract

Our group has designed and developed 3-alkyl-2-vinylindoles as a new type of vinylindoles, which have displayed versatile reactivity in Brønsted acid catalyzed reactions. For instance, this class of vinylindoles can act as 2C building blocks in [n+2] cyclizations, as 2,3-disubstituted indoles in dearomatizations, and as NCC building blocks in [3+2] cyclodimerizations. This article summarizes the main contributions of our group in this research field.

1 Introduction

2 As 2C building blocks in [n+2] cyclizations

3 As 2,3-disubstituted indoles in dearomatization

4 As NCC building blocks in [3+2] cyclodimerizations

5 Summary and outlook

Key words

vinylindole - cyclization - dearomatization - chiral phosphoric acid - organocatalysis

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Referenzen

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