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Synlett 2017; 28(08): 994-998
DOI: 10.1055/s-0036-1588928
DOI: 10.1055/s-0036-1588928
letter
t-BuONa-Mediated Transition-Metal-Free Autoxidation of Diarylmethanes to Ketones
Further Information
Publication History
Received: 29 October 2016
Accepted after revision: 04 December 2016
Publication Date:
30 January 2017 (online)
![](https://www.thieme-connect.de/media/synlett/201708/lookinside/thumbnails/st-2016-w0736-l_10-1055_s-0036-1588928-1.jpg)
Abstract
Autoxidative sp3 C–H transformation of diarylmethanes has been demonstrated using O2-mediation by t-BuONa. This protocol enables an alternative route for the access to diaryl ketones from benzyl derivatives in good to excellent yields under mild reaction conditions, without transition metal catalysts or additional chemical oxidants.
Supporting Information
- Supporting information for this article is available online at http://dx.doi.org/10.1055/s-0036-1588928.
- Supporting Information
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