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Synfacts 2020; 16(02): 0123
DOI: 10.1055/s-0039-1691438
Synthesis of Natural Products and Potential Drugs
© Georg Thieme Verlag Stuttgart · New York

4-(Difluoromethyl)pyridin-2-amine, a Key Intermediate for Lipid Kinase Inhibitors PQR620 and PQR530

Contributor(s):
Philip Kocienski
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Publication History

Publication Date:
21 January 2020 (online)

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Key words

4-(difluoromethyl)pyridin-2-amine - PQR620 - PQR530 - dimethyl formamidines - triazines - Suzuki–Miyaura cross-coupling