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DOI: 10.1055/s-0042-1752659
Photocatalytic Dehydrogenative Amination of Cyclohexanones

Significance
A metal organic layer (MOL) Hf–Ir composite was prepared from a photosensitizing Ir–BBA complex and HfCl4 under solvothermal conditions. A cobaloxime unit was added to the resulting Hf–Ir MOL with a pyridylpropionate (PPA) tether to give Hf–Ir–CoPPA. The Hf–Ir–CoPPA promoted a dehydrogenative amination of cyclohexanones to give the corresponding N-alkyl anilines with photo irradiation by blue LED. The amination of a steroidal 3,17-diketone took place with excellent chemoselectivity to give the corresponding A-ring amination product exclusively.
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Comment
ICP analysis of Hf–Ir–CoPPA revealed that the MOL composite had a Hf/Ir/Co ratio of 1.0/0.54/0.40. A 2D-monolayered double-decker structure of Hf–Ir–CoPPA was constructed with Hf12 cluster units and bridging-ligand units Ir–BBA. Hf–Ir–CoPPA was recovered by centrifugation and reused 8 times without significant loss of its catalytic performance. Hf–Ir–CoPPA also catalyzed the Heck-type coupling of alkyl iodides with styrenes to give the corresponding β-substituted styrenes.
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Publication History
Article published online:
14 April 2023
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