DOI: 10.1055/s-00000131

Synfacts

Issue 05 · Volume 19 · May 2023 DOI: 10.1055/s-013-57327

Synform

A79
Zanda, Matteo: SYNFORM ISSUE 2023/05

Synthesis of Natural Products

z0427
All PDFs of this category
0427
Synthesis of (±)-Vilmoraconitine
0428
Synthesis of (+)-Kopsaporine
0429
Total Synthesis of (+)-Isoneoamphilectane
0430
Synthesis of (+)-Epiibogamine
0431
Total Synthesis of (+)-Zizaene
0432
Total Synthesis of (+)-Stephadiamine
0433
Synthesis of (±)-Ingenol

Synthesis of Heterocycles

z0435
All PDFs of this category
0435
NHC-Mediated Synthesis of γ-Lactams
0436
Organocatalytic Cloke–Wilson Rearrangement to Access Multi-Substituted Furans
0437
Copper-Catalyzed Benzylic sp3 C–H Oxidative Annulation of Ketones and Amines
0438
Robust Synthesis of Functionalized Bicyclic Heteroaromatic Sulfonyl Fluorides
0439
Ruthenium-Catalyzed Synthesis of Piperazines and Diazepanes
0440
Zn-Mediated Synthesis of Pyridines from Alcohols
0441
Practical Arynes from Unfunctionalized Arenes
0442
Versatile Synthesis of 4-Iodopyrrole-2-carbaldehydes
0443
Improved Synthesis of the DLK Inhibitor GDC-0134
0444
Savie: A Biodegradable ‘Drop-In’ Surfactant Replacement for TPGS-750-M
0445
Transformations of Aliphatic Amines and Anilines into Diverse Functionalities
0446
One-Pot Synthesis of N-Functionalized Indoles through a Three-Step Tandem Process
0447
Aerobic Oxidative Cycloaddition Reactions for Pyrazole Synthesis

Synthesis of Materials and Unnatural Products

z0449
All PDFs of this category
0449
From Biphenyl Triflate to Fluorene
0450
Remote C–H Functionalization on Stacked Aromatics
0451
Expanded [23]-Helicene
0452
Hypervalent Iodine Put to Use
0453
Versatile Syntheses of Crowded Trisphosphines
0454
A New T-Type Molecular Photoswitch
0455
Light-Induced Radical-Mediated Minisci Alkylation
0456
Seven- to Eight-Membered Polyene Ring Expansion
0457
The Role of Counteranion in Rhodium Catalysis
0458
One-Pot Synthesis of Degradable Block Copolymers
0459
Radical-Polymerizable Masked Vinylboronic Acids
0460
Room-Temperature C–N Coupling

Metals in Synthesis

z0461
All PDFs of this category
0461
Cutting Me Off: Selective N-Demethylation of Trialkylamines Using C(sp2)–Bromides as HAT Reagents
0462
Synthesis of C-4 Substituted Indoles via Pd-Catalyzed Decarbonylative Cyclization
0463
Highly E- and Z-Selective Hydrogenation of Alkynes Using Chromium and Cyclic Carbene Ligands
0464
Copper-Catalyzed Carbophosphonylation of Styrenes
0465
Pt/Zn-Catalyzed Diborylation of Propargylic Amines
0466
Allylic C(sp3)–H Functionalization of Propylene and Alkenes Catalyzed by a Cationic Iron(II) Complex
0467
Nickel/Photoredox-Catalyzed C(sp3)–H Arylation in the γ-Position of Sulfamate Esters and Amides
0468
Mono-ortho-Alkylation of Meta-Substituted Iodoarenes Using a Cycloolefin Ligand in a Catellani-Type Reaction
0469
Palladium-Catalyzed Rearrangement of 3-Arylcyclobutanones to 1-Indanones
0470
Synthesis of Skipped Trienes via Ni-Catalyzed Bis-Allylation of Alkynes
0471
Rhodium-Catalyzed [4+2+1] Annulation Harnessing the Strain Release of a Methylenecyclopropyl Group
0472
Samarium(II) Iodide-Catalyzed Formal [2π+2σ] Cycloaddition of Bicyclo[1.1.0]butyl Ketones and Alkenes
0473
Dearomative Carboxylation of (Hetero)Arenes with Cesium Formate under Dual Photoredox/HAT Catalysis
0474
Desulfonylative Cross-Electrophile Coupling of Aryl Sulfones and Aryl Bromides under Nickel Catalysis
0475
Nickel-Catalyzed Carbonylation of Alkyl Halides to Acyl Chlorides under Blue Light Irradiation
0476
Pd-Catalyzed Arylation of Furans and Pyrroles Facilitated by Remote Carbonyl Groups
0477
Synthesis of Functionalized Nitriles using a Nickel-Catalyzed Substitution of Allylic Alcohols
0478
Copper-Catalyzed Enantioconvergent C(sp3)–P Cross-Coupling of Secondary Benzyl and Propargyl Bromides
0479
Installation of the Magic Methyl Group onto Heterocycles by Dual Decatungstate Photo-/Nickel Catalysis
0480
Palladium-Catalyzed Enantioselective Synthesis of α-Alkenyl-Substituted 2,3-Dihydrobenzofurans
0481
Synthesis of Thioethers via Ni-Catalyzed Cross-Coupling of Alkyl Thiols with Aryl or Alkenyl Triflates
0482
Enantioselective Synthesis of Allylsilanes by Nickel-Catalyzed Hydrosilylation of 1,1-Disubstituted Allenes
0483
Nickel-Catalyzed Synthesis of Enantioenriched Tertiary Alcohols via DyKAT Processes
0484
Ligand-Controlled Stereodivergent Allylic C(sp3)–H Arylation under Dual Photoredox/Nickel Catalysis
0485
Copper-Catalyzed Enantioselective Dienolate Additions to Aldehydes
0486
Palladium-Catalyzed [4+2] Annulation to Access [6.7]-Fused N-Heterocycles
0487
The Fürstner Indole Synthesis: Titanium-Catalyzed Intramolecular McMurry-Type Carbonyl Coupling

Polymer-Supported Synthesis

z0489
All PDFs of this category
0489
Photocatalytic Dehydrogenative Amination of Cyclohexanones
0490
Hydrogenation of Benzofurans, Indoles, and Benzothiophenes by Co/Co3O4 Core-Shell NPs on Silica
0491
Oxidative Transformation of Silanes Using a Cobalt Catalyst, Supported on N-Doped Porous Carbon
0492
Asymmetric Michael Addition Catalyzed by Chiral-Diamine-Modified Ni Nanoparticles on SiO2
0493
Aziridination and Oxyamination of Styrenes with a Single-Atomic Cobalt Catalyst
0494
Oxidative Coupling of Phenols and Alkenylphenols with TiO2 under Visible Light Irradiation
0495
Exhaustive Hydrogenation of Esters and Carboxylic Acids to Alkanes with a Heterogeneous Pt Catalyst
0496
Semihydrogenation of Alkynes Promoted by a 2D Palladium Metallenes Loaded on Niobium Carbide
0497
Enantioselective Synthesis of Quaternary Tryptolines by a Polystyrene-Supported Phosphoric-Acid Catalyst
0498
Nanocrystal Facet Effects of Ceria in Pd/CeO2 Catalysts for Oxidation of Benzyl Alcohols
0499
β-Selective Furanosylation of α-Furanosyl Fluoride Donors Inside Resorcin[4]arene Supramolecular Capsule

Organo- and Biocatalysis

z0501
All PDFs of this category
0501
Visible-Light Photocatalysis Enables Anti-Markovnikov Hydrofunctionalization of α-Olefins
0502
Breaking Symmetry: Dynamic Kinetic Resolution Enables Organocatalytic Synthesis of Dual-Axial Compounds
0503
Transition-Metal-Mimicking Behavior of New Cationic Constrained Phosphine Species
0504
Chiral Phosphoric Acid Permits Desymmetrizing Hydrolysis of Oxidatively Generated S(VI) Dichlorides
0505
Peptide Catalysis Permits Asymmetric Conjugate Addition of Aldehydes to α-Substituted Vinyl Triflones
0506
Aldol-Type Reaction of α,α-Difluoromethyl Ketones Catalyzed by an Organosuperbase
0507
Dual-Role Disulfide-Catalyzed Intramolecular Hydroamination through N–H Activation
0508
Imine Reductase for the Synthesis of Pharmaceutically Relevant Amines

Innovative Drug Discovery and Development

z0509
All PDFs of this category
0509
Bicycloheptanes as meta-Substituted Arene Bioisosteres
0510
Utilizing Kinetic Modeling for the Conservative Prediction of Dialkyl-N-Nitrosamine Formation
0511
Synthesis of Novel (±)-Lysergic Acid Derivative 12-Chlorolysergic Acid
0512
Aptamer-LYTACs Access Tissue-specific Targeted Degradation
0513
Chemoenzymatic Synthesis of Cepafungin I and Its Analogs
0514
Enantioselective Synthesis of Drug Precursors by Photo-HAT and Facially Selective Radical Capture
0515
Continuous-Flow Process For Safe Formation and Direct Use of Aryldiazoacetate in Cyclopropanation
0516
Introduction of a Potent and Selective JNK2 Inhibitor
0517
Shining Light on Aryl Nitrenes
0518
General BCP-Wing C–H Activation and Rapid Access to Diverse Bridge-Substituted Arene Bioisosteres
0519
Ultralow Band Gap Conjugated Polymers Serve As Photothermal Therapeutic Agents
0520
Synthesis Confirming Structure: The Lobelia Alkaloids

Peptide Chemistry

z0521
All PDFs of this category
0521
Ir-Catalyzed Enantio- and Diastereoselective Synthesis of 3-Substituted Proline Derivatives
0522
Iodide-Mediated Amidation Reaction under Electrochemical Conditions
0523
Photochemical Synthesis of Unnatural Amino Acids through CF3 Radical Addition to Michael Acceptors
0524
Synthesis of Quaternary-Substituted α-Amino γ‑Butyrolactams
0525
Pd and Cu Synergistic Catalysis for the Synthesis of α,α-Disubstituted Amino Acids
0526
Synthesis of Fluorinated Non-Canonical Peptides from α-Fluorinated Carboxylic Acid
0527
β,γ,δ,ε-Amino Acid Synthesis by Photocatalytic Carboxylation with CO2
0528
Arylation of Short Peptides Using a Palladium Catalyst
0529
Deprotection of 2,2-Dimethyl-2-(o-nitrophenyl)acetyl (DMNA) Group in Amino Acids and Peptides

Flow Chemistry

z0531
All PDFs of this category
0531
Effects of Different Substituents on the Regioselectivity of a Photocascade Reaction in Continuous Flow

Erratum

0532
Lin, W; You, L; Yuan, W; He, C: Erratum: Cu-Catalyzed Hydrogermylation of Dehydro Amino Acids