Download PDF
Synfacts 2023; 19(03): 0279
DOI: 10.1055/s-0042-1753309
Polymer-Supported Synthesis

Cross-coupling of Cinnamyl Bromides and Alkyl Boronates Catalyzed by a Pd-Fe MOF

Contributor(s):
Yasuhiro Uozumi
,
Shusuke Hattori
Miguel-Casañ E, Darawsheh MD, Fariña-Torres V, Vitórica-Yrezábal IJ, Andres-Garcia E, Fañanás-Mastral M, *, Míngez Espallargas G. * Universidad de Valencia, Paterna and Universidade de Santiago de Compostela, Spain
Heterometallic Palladium–Iron Metal–Organic Framework as a Highly Active Catalyst for Cross-Coupling Reactions.

Chem. Sci. 2023;
14: 179-185
DOI: 10.1039/d2sc05192c
CrossrefPubMedSearch in Google Scholar
› Further Information
 
 PDF Download Permissions and Reprints

Key words

heterometal - palladium - iron - metal-organic framework

Significance

A heterometallic palladium–iron metal-organic framework (Pd-Fe-MOF) was prepared according to equation 1. Pd-Fe-MOF catalyzed the allylic alkylation of cinnamyl bromides with alkylboronic pinacol esters in the presence of Cs2CO3 and KF to afford the corresponding coupling products in ≤76% yield (eq. 2).


#

Comment

Pd-Fe-MOF was characterized by means of PXRD, single-crystal XRD, XPS, TGA, FT-IR, SEM, EDS, ICP-MS and N2, CO2, CH4 gas adsorption isotherm analyses. In the coupling reaction between cinnamyl bromide and phenylboronic acid pinacol ester, Pd-Fe-MOF was recovered and reused three times without significant loss of its catalytic activity.


#
#

Publication History

Article published online:
13 February 2023

© 2023. Thieme. All rights reserved

Georg Thieme Verlag KG
Rüdigerstraße 14, 70469 Stuttgart, Germany


   Permissions and Reprints