DOI: 10.1055/s-00000131

Synfacts

Issue 03 · Volume 19 · March 2023 DOI: 10.1055/s-013-56656

Synform

A44
Zanda, Matteo: SYNFORM ISSUE 2023/03

Synthesis of Natural Products

z0213
All PDFs of this category
0213
Synthesis of (+)-Alterbrassicicene C
0214
Synthesis of (+)-Candol A, (+)-Powerol A and (–)-Trachinol
0215
Total Synthesis of (+)-Luminamicin
0216
Synthesis of (–)-GA18 Methyl Ester
0217
Total Synthesis of (+)-Neobraclactone C
0218
Total Synthesis of the Alkaloid (±)-Puberuline C
0219
Total Synthesis of (+)-Maritimol

Synthesis of Heterocycles

z0221
All PDFs of this category
0221
Dearomative Redox-Neutral Strategy for the Selective meta-Functionalization of Pyridines
0222
Ni-Catalyzed Synthesis of 2-Heteroaryl Azetidines
0223
Synthesis of Anilines from Boronic Acids
0224
Rhodium-Catalyzed Cross-Coupling to Form Ketones
0225
Gram-Scale Synthesis and Characterization of HAT
0226
Selective Approach to 1,3-Oxazines via Controlled Amino-Diazidation and Amino-Iodoazidation of Alkenes
0227
Synthesis of Imidazo[1,5-a]pyridines via Anomeric Stereoauxiliary Cleavage of d-Glucosamine
0228
Bench-Stable Reagents for Introduction of Highly Lipophilic Thiofluoroalkyl Fragments
0229
Perfluoroalcohol Solvent-Promoted Inverse Electron Demand Diels–Alder Reactions
0230
Ring Expansion of Isoxazoles using Cu(I) Catalysis
0231
Selective meta-Halogenation of Pyridines
0232
[2+2] Cycloadditions to Access sp3-Rich Spirocycles
0233
Synthesis of Pyrazolo[5,1-c][1,4]oxazine Derivatives from 2,2-Dichlorovinylacetophenones

Synthesis of Materials and Unnatural Products

z0235
All PDFs of this category
0235
Trifunctional Lewis Pair Catalyzed Cyclopolymerization
0236
Möbius Cyclophenylenes
0237
BN-Doped Graphenoid Nanoribbons
0238
2-Thioquinolines from Cascade Radical Cyclization
0239
Dehydrofluorination of Phosphinines
0240
Furan-Assisted Cyclization to Prepare Naphthalenophanes
0241
Cu(I)-Catalyzed Cascade Synthesis of Benzo[b]fluorenes
0242
A Large Planar N,S-Heterocycloarene
0243
N→B-Bridged Quasi-[7]circulenes
0244
Catalyst-Free Arene C–H Borylation
0245
Lock the Fickle Macrocycle
0246
Ring-Expansion from Tellurophenes to Telluropyrans

Metals in Synthesis

z0247
All PDFs of this category
0247
Copper-Catalyzed Selective C–H Carboxylation of Alkenes with CO2
0248
Wacker Oxidation of Methylenecyclobutanes to Cyclopentanones via a Semi-Pinacol-Rearrangement
0249
Turning Carbocycles into N-Heterocycles by Cobalt-Catalyzed Nitrogen Atom Insertion
0250
Gold-Catalyzed Thioamination of Terminal Alkynes with Sulfenamides
0251
Cyclopropanols as a Source for Alkylation of 1-Arylpyrazole via Rhodium-Catalyzed C–H Activation
0252
Palladium-Catalyzed Sequential Cyclization for Polycyclic Scaffold Synthesis
0253
C3-Alkylation of Indoles via Ru-Catalyzed Transfer Hydrogenation and Borrowing Hydrogen Approaches
0254
Atroposelective Iron-Catalyzed Coupling between Naphthols and Indoles
0255
Synthesis of Aminobicyclo[3.1.1]heptanes by a Photoinduced Intermolecular [3σ+2σ] Cycloaddition
0256
Ligand Control in the Synthesis of cis-and trans-1,3-Dienes Using Dual Nickel/Photoredox Catalysis
0257
C(sp3)–H Allylation of Alkanes with in situ Formed Carbenes to Access Allylic Quaternary Carbon Centers
0258
Indolo[2,3-b]indoles Syntheses via a Copper-Catalyzed Reaction Using (Aryl)(Mesityl)Iodonium Salts
0259
Copper-Catalyzed Synthesis of Enantioenriched β2,3,3-Amino Acids
0260
Make Your Choice: Ligand-Dependent [2+2] and [4+2] Cycloaddition Reactions of 1,3-Dienes and Alkynes
0261
Regioselective Alkene-Hydroamidation Using Dioxazolones and Isopropanol Under Rhodium Catalysis
0262
Regioselective Hydroacylation of Alkenes via Triple Photoredox/Cobalt/NHC Catalysis
0263
Lewis Acid-Promoted Asymmetric Dearomatization of Pyridines with Grignard Reagents under Cu(I) Catalysis
0264
Desulfurization of Thioamides to Amines or Imines by Manganese-Catalyzed Hydrogenation
0265
Asymmetric Tandem Copper- and Iridium-Catalyzed Reaction for the Construction of 1,3-Chiral Centers
0266
A Three-Component Asymmetric Synthesis of 1,3-Diamines under Relay Amine and Palladium Catalysis
0267
Photoinduced Nickel-Catalyzed Cross-Coupling of Aryl Bromides with Phthalimido Trifluoroethanol
0268
Asymmetric Synthesis of Oxazoline-Spiroketals via Iridium-Catalyzed Domino Allylation/Spiroketalization
0269
Synthesis of Esters via Manganese-Catalyzed Alkoxycarbonylation of Alkyl Chlorides
0270
Asymmetric Intramolecular Reductive Coupling of Imines and Alkenes under Nickel Catalysis
0271
Palladium-Catalyzed Enantioselective Allylic C–H Amination of Alkenes Induced by Blue Light
0272
Novel Access to β‑Carboline-1-one Derivatives via Ru(II)-Catalyzed Annulation of Indole-2-Carboxamides
0273
Access to Chiral Succinimides by Rhodium-Catalyzed Asymmetric Transfer Hydrogenation
0274
Nickel-Catalyzed Synthesis of Polycyclic Imidazoles via Catalyst-Controlled endo-Selective Cyclization
0275
Asymmetric Zirconium-Catalyzed Alkylalumination of Alkenes

Polymer-Supported Synthesis

z0277
All PDFs of this category
0277
One-Pot Synthesis of Allyl- and Alkylamines through A3 Coupling with a Silica-Supported Ru/Cu-Bimetallic Catalyst
0278
Synthesis of Cyclic Carbonates from Epoxides Using Silica-Supported Salophens and Salens
0279
Cross-coupling of Cinnamyl Bromides and Alkyl Boronates Catalyzed by a Pd-Fe MOF
0280
Conjugated Microporous Polymers as Photocatalysts for Hydroxylation of Phenylboronic Acids
0281
[3+2] Cycloaddition of Cyanoarenes and NaN3 with a Mesoporous Silica-Supported Lanthanum Complex
0282
C–H Activation of 2-Arylbenzoxazinones by a Heterogeneous Magnetic Palladium Catalyst
0283
Controllable Cyclization Reactions of Isonitriles Using a MOF-Based Palladium Catalyst
0284
Switchable Perfluoroalkylation of Terminal Alkynes Promoted by Mesoporous Graphitic Carbon Nitride
0285
Hydro(Deutero)dehalogenation of Aryl Bromides by Water as a Reductant and a Hydrogen Source
0286
Friedel–Crafts Alkylation between Indoles or Pyrroles and β-Nitrostyrenes Using La(III)-Based MOF
0287
Synthesis of Disulfides through Dehydrogenative Dimerization of Thiols Promoted by Zeolite ETS-10

Organo- and Biocatalysis

z0289
All PDFs of this category
0289
Chiral Pyridoxal–Gold Rush in Asymmetric Carbonyl Catalysis
0290
Sulfonium-Based EDA Complexes Grant Access to Electronically Diverse Aryl Radicals
0291
Organocatalytic/Photochemical Approach to Regioselective Functionalization of Azines
0292
Radical-Based 1,4-Difunctionalization of Two Electronically Differentiated Olefins
0293
A Chemo-Enzymatic Dearomatization Cascade Approach to Enantioenriched Piperidines from Pyridines
0294
Hydroalkylation of Olefins Mediated by Photochemically Generated NHC-Ligated Boryl Radicals
0295
Photocatalytic Radical Addition to N-Sulfonyl Hydrazones as a C–H Alkylation Strategy
0296
Organocatalysis Enables the Isotopic Labelling of Amino Acids
0297
Organocatalytic Hydrophosphonylation Towards Enantioenriched Self-Recognizing Ureidophosphonates
0298
Chiral Phosphoric Acid- and Photoredox-Catalyzed Enantioselective Giese Additions of α-Amino Radicals

Innovative Drug Discovery and Development

z0299
All PDFs of this category
0299
Expanding the Toolbox of Cysteine-Reactive Probes
0300
Structurally Guided Synthesis and Development of Novel Macrocyclic Antibiotics
0301
High-Level Data Fusion Leads to the Discovery of a General Atropselective Iodination Catalyst
0302
Raise the ALARM: An Enzyme-Controlled, Light-Activated RNA Modification Approach
0303
Synthesis of an Improved Enterobactin–Muraymycin-Drug Conjugate Against Gram-Negative Bacteria
0304
Small Molecule SST2 Agonist as a Potential Therapeutic for Acromegaly and Neuroendocrine Tumors
0305
Discovery of Selective Inhibitor and Degrader of Mutant PI3Kα
0306
Modular Total Synthesis of Antibacterial Nucleosides
0307
Concise and Scalable Synthesis of Thalidomide
0308
Development of Potent and Selective Dual Cyclin-Dependent Kinase 7 and 9 Inhibitors
0309
Potent and Selective PARP7 Inhibitor, KMR-206, Regulates IFN-I Signaling
0310
Harnessing Biocatalytic Cascades to Access Pharmaceutically Relevant Piperidines

Peptide Chemistry

z0311
All PDFs of this category
0311
Cu-Catalyzed Introduction of Oxime Ethers into Peptides
0312
Rh/Chiral Phosphoric Acid Cocatalyzed Synthesis of N-(Anthrancen-9-ylmethyl) Isoserines
0313
Squaramide-Catalyzed Amino Acid Induced Tetrahydro-β-Carboline Synthesis
0314
Visible-Light Photocatalysis for the Synthesis of Quaternary Alkynyl α‑Amino Esters
0315
Photoinduced Coupling Reaction of Glycine Derivatives with N-Alkoxyphthalimides
0316
Synthesis of Unnatural Amino Acids from Glycinates
0317
Cu-Catalyzed Borylamination for the Synthesis β-Boryl-α-amino Esters
0318
Chiral Aldehyde-Ni Dual-Catalyzed α-Propargylation to α-Amino Acids
0319
One-Pot Synthesis of N-Methyl Dipeptides from Amino Acid-Derived Oxazolidinones

Flow Chemistry

z0321
All PDFs of this category
0321
A Safe and Mild Protocol for the Synthesis of Dithiocarbamates under Continuous Flow Conditions