Download PDF
Synfacts 2006(9): 0911-0911  
DOI: 10.1055/s-2006-949242
Metal-Catalyzed Asymmetric Synthesis and Stereoselective Reactions
© Georg Thieme Verlag Stuttgart · New York

Iridium-Catalyzed Hydrogenation

Contributor(s): Hisashi Yamamoto, Joshua P. Abell
S. Nanchen, A. Pfaltz*
University of Basel, Switzerland
Further Information

Publication History

Publication Date:
23 August 2006 (online)

    Permissions and Reprints

Significance

Recent advances in asymmetric hydrogenation have shown almost perfect enantio­selectivities on a wide range of substrates even with simple olefins. Previously reported N-heterocyclic carbene (NHC) ligands with iridium (by Burgess and co-workers) have inspired others to increase the performance of the reaction to the most active P,N-ligands.