Subscribe to RSS
Please copy the URL and add it into your RSS Feed Reader.
https://www.thieme-connect.de/rss/thieme/en/10.1055-s-00000131.xml
Synfacts 2006(11): 1130-1130
DOI: 10.1055/s-2006-949447
DOI: 10.1055/s-2006-949447
Metal-Catalyzed Asymmetric Synthesis and Stereoselective Reactions
© Georg Thieme Verlag Stuttgart · New York
Ruthenium-Catalyzed Enzymatic Dynamic Kinetic Resolution of Diols
B. Martín-Matute, M. Edin, J.-E. Bäckvall*
Stockholm University, Sweden and Universidad Autónoma de Madrid, Spain
Further Information
Publication History
Publication Date:
24 October 2006 (online)
Significance
Enzymatic kinetic resolution remains the method of choice for generation of enantiopure starting materials for the elaboration to other compounds. This represents an efficient method for generating enantiomerically pure diacetylated diols. This novel enzyme-metal-catalyst combination efficiently transforms optically inactive mixtures to optically pure products in high yields.