DOI: 10.1055/s-00000131

Synfacts

Issue 04 · Volume 8 · April 2012 DOI: 10.1055/s-002-23000

Synform

A30
Zanda, Matteo: SYNFORM ISSUE 2012/04

Synthesis of Natural Products and Potential Drugs

z349
All PDFs of this category
0349
Synthesis of (±)-Meloscine
0350
Synthesis of AMD15548
0351
Synthesis of LY2784544
0352
Synthesis of Entecavir (BMS-200475)
0353
Synthesis of (+)-Lactiflorin
0354
Synthesis of BMS-665053
0355
Synthesis of Nilotinib
0356
Synthesis of (±)-Maistemonine, (±)-Stemonamide, and (±)-Isomaistemonine
0357
Synthesis of an HCV NS5B Polymerase Inhibitor
0358
Synthesis of (–)-Stenine
0359
Synthesis of (–)-Okilactomycin D
0360
Synthesis of SN-38
0361
Synthesis of (+)-Ambrisentan
0362
Total Synthesis of (–)-Apicularen A
0363
Total Synthesis of Carolacton
0364
Synthesis of CEP-28122

Synthesis of Heterocycles

z365
All PDFs of this category
0365
One-Pot Synthesis of Cannabinoids via In-verse-Electron-Demand Diels–Alder Reaction
0366
Ru-Catalyzed Synthesis of Isocoumarins from Benzoic Acids and Alkynes
0367
Modular Access to 2-Substituted Pyridines via Suzuki Cross-Coupling of MIDA Boronates
0368
Synthesis of Benzo[a]quinolizines by a MCR/Allylation/Heck Sequence
0369
Indoloquinolizines from a One-Pot, 12-Step, Three-Component Cascade Reaction
0370
Heterocyclo[3.3.1.0]nonanes by Pt-Catalyzed Cycloisomerization of Allyl Alkynes
0371
Synthesis of Isochromanones and Isoquinolines via Friedel–Crafts Cyclization
0372
Pd-Catalyzed Synthesis of Indolo[1,2-a]-Quinoxalines
0373
Catalytic Oxidative Synthesis of Quinazolines and Benzoxazines
0374
Cyclocarbonylation of Enynes Using Glyceraldehyde as a Carbonyl Source
0375
A Domino Radical Smiles Rearrangement Approach to Indolin-2-ones
0376
Annulation–Electrophilic Amination Approach to 3-Aminobenzofurans and -indoles
0377
Oxidative Rearrangement Approach to Fused Imidazolines and Quinazolines
0378
Polysubstituted Oxazoles via Cerium(III)-Promoted Cyclization of Propargyl Amides
0379
Synthesis of Thieno[3,2-c]pyridinones by Cyclopropyl Thione Rearrangement

Synthesis of Materials and Unnatural Products

z381
All PDFs of this category
0381
Triazoles for Multidentate Halogen Bonding
0382
Self-Assembly of Polydiacetylene-Peptide Nanostructures
0383
Synthetic Nanotube from Topochemical Polymerization
0384
First Synthesis of Poly(diaminosulfide)s
0385
Scholl with a Twist
0386
A New Class of Proton Sponge
0387
Tunable Cyclic Indole Tetramers
0388
From ‘Solid Hydrazine’ to Solid-State Azines
0389
Bottom-Up Templating of Carbon Nanotubes
0390
Rapid Access to Benzobistriazole Building Blocks
0391
Iron Catalysts Promote Efficient Regioselective Hydrosilylation of Alkenes
0392
Tribenzotriquinacene Benzyne
0393
Linear and Trigonal Pyrazinacenes

Metal-Catalyzed Asymmetric Synthesis and Stereoselective Reactions

z395
All PDFs of this category
0395
Enantioselective Hydrogenation of (1-Chloro-1-Alkenyl) Boronic Esters
0396
Gold-Catalyzed Enantioselective Dehydrative Allylic Amination
0397
Iron-Catalyzed Intramolecular Allylic C−H Amination
0398
Asymmetric Conjugate Addition of Me3Al to β,γ-Unsaturated α-Keto Esters
0399
Copper-Catalyzed Asymmetric Allylic Substitution of Enyne Chlorides
0400
Asymmetric Cyanation of Nitroalkenes Catalyzed by a Salen–Titanium Catalyst
0401
Palladium-Catalyzed Intramolecular Asymmetric Allylic Alkylation
0402
Asymmetric Decarboxylative Allylic Alkylation of N-Heterocycles
0403
Copper(I)-Catalyzed Asymmetric Carbenoid Insertion into Phenolic O–H Bonds
0404
Diastereoselective Hydrogenation of α,β-Epoxy and Aziridinyl Ynones
0405
Asymmetric Cycloadditions of Trimethylenemethane with Nitroalkenes
0406
Asymmetric Synthesis of 1,2-Diols
0407
Enantioselective 1,2-Addition to α-Diketones
0408
Diastereoselective Synthesis of Enantiopure β-Trifluoromethyl β-Amino Alcohols
0409
Selective NHC–Cu-Catalyzed Allylic Substitution
0410
Copper-Catalyzed Asymmetric Conjugate Addition of Nitroalkanes
0411
Catalytic Asymmetric Diels–Alder Cycloaddition of Fluorinated Acrylates
0412
Iridium-Catalyzed Asymmetric Hydrogenation and Spiroketalization
0413
Ir-Catalyzed Asymmetric Hydrogenation of β-Aryl β-Keto Esters
0414
Asymmetric α-Oxidation of Aldehydes
0415
Alkylative Ring Opening of Chiral Aziridines
0416
One-Pot Catalytic Enantioselective Synthesis of Homoallylboronates
0417
Expanded Scope of 1,6-Addition of Arylboroxines via Ligand Tuning
0418
Asymmetric Cu-Catalyzed Conjugate Addition Followed by Amidomethylation
0419
Asymmetric Relay Friedländer Condensation–Transfer Hydrogenation
0420
Rh-Catalyzed Asymmetric Arylation of N-(tert-Butanesulfinyl)imines
0421
Copper-Catalyzed Asymmetric Alkene Amination–Heck-Type Coupling Cascade
0422
Rhodium-Catalyzed Enantioselective 1,2-Addition of Arylboronic Acids
0423
Ir-Catalyzed Dearomatization of Pyrroles via Allylic Substitution Reaction
0424
Enantioselective Intramolecular Allylation of Amines

Metal-Mediated Synthesis

z425
All PDFs of this category
0425
Novel Difluoromethylation Reagent
0426
Heteroarylation of Azine N-Oxides
0427
anti-Carbobismuthination of Alkynes
0428
Direct Allylation of Inert Amide Carbonyls
0429
Silver-Catalyzed Azidation of Allylic Alcohols
0430
Palladium-Catalyzed Aryltrifluoromethylation of Alkenes
0431
Sequential Ir-Catalyzed Borylation and Cu-Catalyzed Trifluoromethylation of Arenes
0432
Zinc-Mediated Highly α-Regioselective Prenylation of Imines
0433
Asymmetric [3+2] Annulation of Allylsilanes with Isatins
0434
Copper-Catalyzed Perfluoroalkylation of Arenes and Aryl Bromides
0435
Cyclopentanol Synthesis via Three-Component Coupling
0436
Reduction of Carboxylic Acids Using SmI2–H2O–Et3N
0437
Synthesis of Hydrazide Linked Alkynes (Ynehydrazides)
0438
Rhodium(I)-Catalyzed Borylation of Aryl and Alkenyl Nitriles
0439
n-BuLi-Initiated Ring-Opening Cyclization of Cyclopropene Derivatives

Organo- and Biocatalysis

z441
All PDFs of this category
0441
Eosin Y Promoted C–H Arylation of Heteroarenes with Aryl Diazonium Salts
0442
Inverse-Electron-Demand Diels–Alder Reaction to Construct Azaspirocycles
0443
A Powerful Catalyst for Asymmetric Intermolecular Stetter Reaction
0444
Thiourea-BINOL Catalyzed Three-Component Petasis Reaction
0445
Enantiodivergent and γ-Selective Asymmetric Allylic Amination
0446
Secondary Amine Catalyzed Oxidation of Alcohols to Enals
0447
Mild CO2 Fixation by Using PMHS and Catalytic NHCs
0448
Cinchona-Catalyzed Asymmetric Heterodimerization of Ketenes
0449
One-Pot Synthesis of Optically Active Thiophenes
0450
[2+2] Cycloadditions via H-Bond Directing Dienamine Catalysis
0451
Asymmetric α-Alkylation of Ketones by Brønsted Acid Catalysis
0452
Phosphine-Based Organocatalysis towards α-Amino Acid Derivatives

Polymer-Supported Synthesis

z453
All PDFs of this category
0453
Synthesis of Primary Amines with OMS-2
0454
Preparation of Thiophenylalanine-Containing Peptides
0455
Mesoporous Polymer-Supported Organometallic Catalysts
0456
Sequential Sonogashira Coupling–Cyclization Reaction with CuO–Fe3O4
0457
Reduction of Nitroarenes and Epoxides with AgNPs@CeO2
0458
Cyanation with K4[Fe(CN)6] by Hydroxyapatite-Supported Cu(I)
0459
Aerobic Oxidation of Alcohols with AuNPs in Polymer Matrices
0460
[4+2] Benzannulation with a Nanoporous Gold Catalysts
0461
Solid-Phase Synthesis of Aminobenz-imidazole-Tethered Thiazoles
0462
Aminocarbonylation of AryI Iodides Using MOF-5-Supported Pd Nanoparticles
0463
Michael Addition with Bifunctional Polymeric Organocatalysts
0464
Arylation of Unactivated Arenes with a MOF-253 Catalyst
0465
Addition of Alkynes to Aldehydes Using TiO2-Supported Ag Nanoparticles