DOI: 10.1055/s-00000131

Synfacts

Issue 02 · Volume 9 · February 2013 DOI: 10.1055/s-003-24367

Synform

A15
Zanda, Matteo: SYNFORM ISSUE 2013/02

Synthesis of Natural Products and Potential Drugs

z119
All PDFs of this category
0119
Synthesis of a Glucagon Receptor Antagonist
0120
Synthesis of (±)-Maoecrystal V
0121
Total Synthesis of (±)-Alstilobanine A
0122
Isolation and Total Synthesis of Voacangalactone
0123
Total Synthesis of (±)-Limaspermidine and (±)-1-Acetylaspidoalbidine
0124
Synthesis of SNX-5422
0125
Synthesis of a MAP Kinase Inhibitor
0126
Synthesis of Acetyl-CoA Carboxylase Inhibitors
0127
Total Synthesis of Acetylaranotin via Rhodium-Catalyzed Cycloisomerization
0128
Synthesis of AZD1981
0129
Synthesis of Imatinib
0130
Synthesis of a Dual BACE1/CYP3A4 Inhibitor
0131
Synthesis of a BACE1 Inhibitor
0132
Total Synthesis of Acetylaranotin via Baeyer–Villiger Oxidation
0133
Synthesis of (±)-Gomerone C
0134
Synthesis of SCH 900229
0135
Synthesis of a BACE1 Inhibitor

Synthesis of Heterocycles

z137
All PDFs of this category
0137
Concise Synthesis of Complex Polycyclic Lactams
0138
Copper-Catalyzed Heteroannulation to Tetrahydroxanthen-1-ones
0139
Palladium-Catalyzed Asymmetric Synthesis of Cyclopropane-Fused Quinoline Derivatives
0140
Iron(II) Chloride-Catalyzed Synthesis of Imidazo[1,2-a]pyridines
0141
Palladium-Catalyzed Carbonylative Annulation to Flavones
0142
Domino Staudinger–Aza-Wittig Synthesis of 1H-Pyrazolo[1,5-b]indazoles
0143
Robust Nickel-Mediated Methodology for the Cross-Coupling of Heterocycles
0144
Synthesis of Dipyrido[1,2-a:3′,4′-d]imidazole Salts from 2-Aminopyridine
0145
Palladium-Catalyzed Intramolecular C(sp3)–H Alkenylation Route to Hexahydroindoles
0146
PIDA-Mediated Intramolecular Oxidative Cyclization of Enamides to Oxazoles
0147
Synthesis of Benzimidazoles and Quinazolinones via Pd-Catalyzed Heteroannulation
0148
Synthesis of Benzazoles Using S8 as the Oxidizing Agent
0149
Snieckus, Victor; Zhao, Yigang: Synthesis of Phenanthridinones via C–H Activation of N-Methoxybenzamides

Synthesis of Materials and Unnatural Products

z151
All PDFs of this category
0151
Reactions of Arynes with Phenols: Helicene Formation and ortho-Arylation
0152
Cascade Cyclizations Yielding Polyaromatic Products
0153
The Hexadehydro-Diels–Alder Reaction – A New Method Yielding Benzenoids
0154
Oligoarenes by Chain-Growth, Radical/Anionic Polymerization
0155
Iron-Catalyzed Polymerization of Isoprene and Other 1,3-Dienes
0156
Nucleophilic Trifluoromethylation Using Fluoroform
0157
Azaboradibenzo[6]helicene via Tandem Friedel–Crafts Reaction
0158
Acidic Oxidation of Aromatic Amines Yields Fused Azacene Heterocycles
0159
Efficient Synthesis of Conjugated Polymers with Pd/C Catalysis
0160
Heteroatom-Free Donor–Acceptor Copolymers
0161
Accessing ortho-Polyphenylenes Directly from Poly(phenylene ethynylene)s
0162
Bridged Azacalixarenes

Metal-Catalyzed Asymmetric Synthesis and Stereoselective Reactions

z163
All PDFs of this category
0163
Copper-Catalyzed Asymmetric Boration
0164
Dissymmetric Diarylideneacetone Synthesis via Palladium Catalysis
0165
Cobalt-Mediated Asymmetric 1,6-Alkyne Addition to Conjugated Carbonyls
0166
Iridium-Catalyzed Asymmetric Ring-Opening of Oxabenzonorbornadienes
0167
Palladium-Catalyzed Asymmetric Allenylation of Malonates
0168
Enantioselective Allylic Substitution with Alkylboranes
0169
Gold-Catalyzed Enatioselective Transfer Hydrogenation of Quinolines
0170
Rhodium-Catalyzed Asymmetric 1,4-Additions in Water
0171
Asymmetric Synthesis of α-Hydroxy Ketone Derivatives
0172
Silver-Catalyzed Azomethine Ylide Cycloaddition
0173
Rhodium-Catalyzed Asymmetric Hydrogenation
0174
Gold-Catalyzed Allene–Ene [2+2] Cycloaddition
0175
Highly Stereoselective Synthesis of 4-OH-Tetrahydropyrans Using Iron(III) Catalysis
0176
An Atom-Efficient Osmium-Mediated Dihydroxylation Using Hydrogen Peroxide
0177
Synthesis of All-Carbon Quaternary Centers by Rhodium-Catalyzed Allylic Substitution
0178
TADDOL-Based Ligands in Enantioselective Copper-Catalyzed Additions
0179
Iron-Catalyzed Biomimetic Oxidation of Cafestol to Tricalysiolide B
0180
Asymmetric Copper-Catalyzed Intramolecular Indoline Synthesis
0181
Zinc-Catalyzed Enantioselective Desymmetrization of Aziridines
0182
Synthesis of Cyclic Amines Using Stereodefined Allylic N,O-Acetals
0183
Copper–NHC Complexes for the Asymmetric Addition to Acyclic Enones
0184
Dirhodium Carboxylates Catalyzed Three-Component Reaction
0185
Silver-Catalyzed Asymmetric [3+2] Cycloaddition of Azomethine Ylides
0186
Asymmetric Cu-Catalyzed Cyclopropanation of Olefins
0187
C(sp3)–H Insertions with Donor Rhodium Carbenoids
0188
Asymmetric Allylic Amination of Unactivated Terminal Olefins
0189
Copper-Catalyzed Propargylic Amination with Primary and Secondary Amines
0190
Diastereoselective Palladium-Catalyzed Tetrahydrofuran Synthesis
0191
Lanthanides-Catalyzed Enantioselective Epoxidation of α,β-Unsaturated Ketones

Metal-Mediated Synthesis

z193
All PDFs of this category
0193
Direct Lithiation of Aryl Chlorides
0194
Direct Alkylation of Pyridyl Alcohols Using Lithium Reagents
0195
Synthesis of Diarylethynyl Methanes via a Multicomponent Coupling
0196
Iron-Mediated Arylation of Quinones and Pyridine Analogues
0197
CuI-Controlled C–C and C–N Bond Formation via C(sp3)–H Activation
0198
Enantioselective Synthesis of Tertiary Propargylic Boronic Esters
0199
Access to (Hetero)Arylethoxy Motifs via Suzuki–Miyaura Cross-Coupling
0200
Copper-Catalyzed Carbozincation of Cyclopropenes with Arylzinc Reagents
0201
One-Pot Synthesis of 1-Iodoalkynes from Benzylic and Allylic Bromides
0202
Copper-Promoted Sulfenylation of C(sp2)–H Bonds
0203
Cobalt-Catalyzed Addition of Arylzinc Reagents to Alkynes
0204
Differentiation between Two Nucleophilic Sites on a Single Aromatic Substrate
0205
Copper-Mediated Difluoromethylation of (Hetero)Aryl Iodides and β-Styryl Halides
0206
Synthesis of Chiral Fluoroalkyl Products via Copper-Free Asymmetric Allylic Alkylation
0207
Copper-Catalyzed Azidation of Anilines

Organo- and Biocatalysis

z209
All PDFs of this category
0209
Organocatalytic Cross-Coupling of Aldehydes
0210
Brønsted Acid Catalyzed Enantioselective [3+2] Cycloaddition
0211
Sequential Amine–NHC-Catalyzed Cycloaddition and Redox Reaction
0212
Asymmetric Diels–Alder Reaction of o‑Quinodimethanes
0213
Palladium–Chiral Amine Co-catalyzed Enantioselective Conjugate Additions
0214
Lewis Base Catalyzed [4+2] Cycloaddition of Acyl Chlorides
0215
A Hetero-Diels–Alder Reaction of an s-trans Diene?
0216
Chiral Phosphine Catalyzed Asymmetric Michael Addition of Oxindoles
0217
Highly Selective Catalyst for Vinylogous and Bis-vinylogous Michael Additions

Polymer-Supported Synthesis

z219
All PDFs of this category
0219
SPPS of Backbone-Fluorinated Peptides
0220
Asymmetric Reduction of Aromatic Ketones Using Immobilized Iridium
0221
Aerobic Oxidation of Alcohols with MoS2/Ta3N5 Nanocomposites
0222
Asymmetric Michael Addition with DACH–Ni-PMO
0223
Asymmetric α-Amination of Aldehydes with Supported Prolinol TBS Ether
0224
A Resin-Supported Co(III)–Salen Catalyst for HKR of Epoxides
0225
Asymmetric Cyanosilylation of Aldehydes by a Helical Polyaminoacid
0226
Synthesis of Peptides Using Cysteine Side-Chain-Anchored Trityl Resin
0227
Aldol Reaction with a Fe3O4 Nanoparticle Supported Proline Catalyst
0228
A Cooperative Catalytic System of PI/CB-Pt/Ir and TTSBI
0229
Hiyama Cross-Coupling with a PS- Supported Palladium Catalyst
0230
Double-Carbonylation of Amines to Oxamides with Au/HT
0231
N-Allylation of Amines with Allylic Acetates Using Cellulose-Supported Palladium
0232
Preparation of Alkynyl Chalcogenides with Cu/Al2O3

Addenda and Errata

0233
Wang, X.; Meng, F.; Wang, Y.; Han, Z.; Chen, Y.-J.; Liu, L.; Wang, Z.; Ding, K.: Formal Synthesis of Ezetimibe
0234
Nishi, T.: Synthesis of DS-8108b