Synfacts
Issue 09 · September 2015
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A120
SYNFORM
ISSUE 2015/09
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Synthesis of Natural Products and Potential Drugs
z897
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0897
Total Synthesis of (–)-Jiadifenolide
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0898
Synthesis of Phthioceranic Acid
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0899
Synthesis of JAK2 Inhibitor BMS-911543
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0900
Synthesis of Trichodermamides A, B, and C
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PDF (113 kb)
0901
Synthesis of CJ-16,264
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PDF (117 kb)
0902
Synthesis of Alisertib
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0903
Total Synthesis of (–)-Amphidinolide P
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0904
Synthesis of a Matrix Metalloproteinase Inhibitor
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0905
Synthesis of (+)-Machaeriol B, (+)-Machaeriol D, (+)-Δ
8
-THC, and Analogues
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PDF (131 kb)
0906
Synthesis of Chk1 Inhibitor GDC-0425
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0907
Synthesis of (
R
)-Ruxolitinib
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PDF (119 kb)
0908
Synthesis of BMS-191011
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0909
Synthesis of Oridamycins A and B
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0910
Chemoenzymatic Synthesis of a Rosuvastatin Building Block
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Synthesis of Heterocycles
z911
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0911
Synthesis of Isoxazolino Phenanthridines
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0912
Morpholines and Spirocyclic Dihydrofurans from Oxetanyl
N
,
O
-Acetals
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0913
Synthesis of Dihydro-1
H
-benzothiazolopyridines by NHC Catalysis
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0914
Azaquinolizinium Salts by Ring-Closing Metathesis
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0915
Formal Hydroamination of Alkenes with Nitro- and Heteroarenes
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0916
Radical-Mediated Annulations of Benzene-Linked 1,
n-
Enynes
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0917
Optimized Process Route to a Benzoxazepine-Derived Kinase Inhibitor
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0918
Metal-Free Synthesis of Perfluorinated Oxindoles
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0919
Selective Synthesis of 3- or 5-Substituted Aminopyrazoles
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0920
7-Azaindoles via Rhodium(III)-Catalyzed C–H Activation–Annulative Coupling
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0921
Aminodifluoromethylation of Unactivated Alkenes
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0922
Stereodivergent Synthesis of Substituted Tetrahydrofurans
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0923
Pyrroles and Oxazines via Cycloaddition of Borodienes with Nitrosoarenes
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0924
A Radical Oxidative Annulation Route to Dihydrofurans and Indolizines
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0925
Synthesis of Benzazoles Catalyzed by Sodium
tert
-Butoxide
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Synthesis of Materials and Unnatural Products
z927
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0927
New CN and CC Group-Transfer Reagents
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0928
A Different Angle
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0929
One Reagent, Three Reactions in One Pot
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0930
Boron Goes Both Ways
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0931
An All-Pnictogen Aromatic
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0932
Organic Traps: Getting Hydrocarbons to Shine
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0933
Two Rings to Rule Them All: Catenated Polyesters via Macrocycle Expansion
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0934
A Greener Path to Bioplastics
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0935
Cages Interlocked by Dynamic Metathesis
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0936
Propellers with Nitrogen: New Propulsion towards 2D Polymers?
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0937
A One-Step Synthesis of Chelating, Alpha-C
2
-Bridged Biphospholes
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0938
A Scratch ‘n’ Shine Polymer
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Metal-Catalyzed Asymmetric Synthesis and Stereoselective Reactions
z939
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0939
Palladacycle-Catalyzed Highly Enantioselective Arylation of Sulfonylimines
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0940
Rhodium-Catalyzed Asymmetric Construction of 3-Hydroxypiperidones
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0941
Copper-Catalyzed Synthesis of Chiral Phosphine Boronates
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0942
Iridium-Catalyzed Asymmetric Hydroalkynylation of Norbornadienes
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0943
Allylic Alkylation of 3-Substituted Indoles
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0944
Asymmetric Allylic Dearomatization of Pyrroles and Controllable Migration
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0945
Enantioselective Copper-Catalyzed Synthesis of Lactones
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0946
Enantioselective Hydroamination of Unactivated Internal Olefins
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0947
Asymmetric Transformation of 3-Isothiocyanatooxindoles
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0948
Copper-Catalyzed Desymmetrative Reaction Forming Chiral O-Heterocycles
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0949
N
,
N
′-Dioxide/Nickel(II)-Catalyzed Asymmetric Hetero-Diels–Alder Reaction
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0950
Enantioselective Synthesis of Allenoates by Copper Catalysis
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0951
Highly Efficient Asymmetric Palladium-Catalyzed Decarboxylative Allylic Alkylation
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0952
Transfer Hydrogenation–Dynamic Kinetic Resolution of α-Alkoxy β-Keto Esters
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0953
syn
-Stereoselective Ring Opening of Oxabenzonorbornadienes
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0954
Enantioselective Synthesis of Isoxazolines by 1,3-Dipolar Cycloaddition
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0955
Regio- and Enantioselective Intermolecular Hydroamination of Alkynes
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0956
Asymmetric Copper-Catalyzed Formal [4+3] Annulation of Cyclopropanes and Dienes
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0957
Regio- and Enantioselective Redox Relay Heck Reactions
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0958
Asymmetric 1,4-Addition Using a Chiral Phosphine–Olefin Ligand
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0959
Cycloheptenes by a Gold-Catalyzed Tandem Alkoxylation–Claisen Rearrangement
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0960
Asymmetric Hydrogenation of Fluorinated Pyrazol-5-ols
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0961
Rhodium(I)-Catalyzed Enantioselective Cycloadditions
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0962
Allyl–Allyl Cross-Coupling of Allylic Carbonates with (
E
)-1,3-Diarylpropenes
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0963
Cinchona Alkaloid Amide/Zinc(II) Catalyzed Mannich Reaction of Ketimines
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0964
Diastereoselective Synthesis of Chromane-4-ones
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0965
Aliphatic α-Amino Acids by Rhodium-Catalyzed Asymmetric Hydrogenation
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0966
Enantioselective Interrupted Feist–Bénary Reaction with Ynones
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0967
Multicomponent Reaction for the Synthesis of γ-Oxo-β-amino Esters
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Metal-Mediated Synthesis
z969
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0969
Directed Iron-Catalyzed C–H Methylation
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0970
Spirocyclization of α-Aminonitriles
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0971
α-Alkylation of α-MIDA Boryl Aldehydes
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0972
Mn(OAc)
3
-Mediated Aerobic Oxidative Decarboxylative Coupling
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0973
Iridium-Catalyzed Borylation of Benzylic C–H Bonds
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0974
Palladium-Catalyzed Monofluoromethylation of Arylboronic Esters
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0975
Copper-Catalyzed Reductive Alkylation of 1,3-Dienes with Alkyl Fluorides
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0976
Lithiation of Azobenzenes
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0977
One-Pot Unsymmetrical Ketone Synthesis
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0978
Asymmetric Arylation of Amino Acids
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0979
Diastereoselective Formation of Alcohols
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0980
Titanium(IV)-Mediated Amination of Aryl Methyl Ethers
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0981
Copper Nitrate Mediated Synthesis of Isoxazolines
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0982
Chemoselective Suzuki–Miyaura Cross-Coupling
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0983
Perfluoroalkyl and -aryl Zinc Ate Complexes in Synthesis
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Organo- and Biocatalysis
z985
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0985
Highly Efficient and Enantioselective Silylation of Alcohols
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0986
Amine-Catalyzed Conjugate Addition of Aldehydes to β-Tosyl Enones
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0987
In Situ Generated
N
-
tert
-Butoxycarbonyl Imines for Mannich Reactions
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0988
Organocatalytic Nazarov–Semipinacol Rearrangement Cascade
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0989
Stereospecific Oxidative C–H Amination Catalyzed by Iodoarenes
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0990
Asymmetric α-Cyanoalkylation of Aldehydes by Photoredox Organocatalysis
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0991
Chiral Phosphoric Acid Catalyzed Nucleophilic α-Amination of Azoalkenes
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0992
Asymmetric Conjugate Peroxidations of α,β-Unsaturated Aldehydes
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0993
Enzymatic Oxidative Decarboxylation of Fatty Acids to 1-Alkenes
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0994
Asymmetric Dearomatization of Pyridines
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Polymer-Supported Synthesis
z995
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0995
Chemoselective Hydrogenation of Aldehydes on Stable Gold Nanoparticles
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0996
Polymer Foam Supported Palladium Nanoparticles for Suzuki Reactions
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0997
Flow Reactors Using Hollow Fibers for Acid, Base, or Chiral Rhodium Catalysis
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0998
Oxidative Condensation of Aldehydes and Amines by Using Gold Nanoparticles
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0999
Synthesis of Imidazoles with TFE/SBA-15-Pr-SO
3
H
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1000
C–N Bond Formation of Secondary Amines with Cobalt/Alumina Catalyst
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1001
Development of a Silica-Supported Ruthenium Bipyridyl Photocatalyst
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1002
N-Arylation of Amines with Arylboronic Acids Using Supported Copper
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1003
Base-Free Copper Powder-Catalyzed Knoevenagel Condensation
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1004
Oxidative Amidation of Alcohols on Iron(III) Hydroxide/Magnetite Nanoparticles
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1005
Controlled Aromatic Nitration with a Poly-(4-vinylpyridine)–Nitrating Mixture Complex
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1006
Continuous-Flow Hydrogenation with Supported Platinum Nanoparticles
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1007
Cycloisomerization of Dipeptides by Using Supported Gold Nanoparticles
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1008
Solid-Phase Synthesis of γ- and δ-Lactams via
N
-Acyliminium Ions
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1009
Reductive Alkylation by Using Calcium Hydride and Palladium on Carbon
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1010
Borylation of Alkyl Bromides by Using Copper(I) Oxide Nanoparticles on Carbon Black
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