DOI: 10.1055/s-00035024

Thrombosis and Haemostasis

Ausgabe 01 · Volume 26 · August 2017 DOI: 10.1055/s-007-35223

Editorial

01
Lip, Gregory Y. H.; Weber, Christian: A happy and prosperous New Year 2017 with “Thrombosis and Haemostasis” …. and our 60th Anniversary!

Invited Editorial Focus

03
Lisman, Ton; Violi, Francesco: Cirrhosis as a risk factor for venous thrombosis

T&H Insight

06
Wojta, Johann: What ADAMTS13 does in the liver…

Review Article

07
Liberale, Luca; Dallegri, Franco; Montecucco, Fabrizio; Carbone, Federico: Pathophysiological relevance of macrophage subsets in atherogenesis

Coagulation and Fibrinolysis

19
Geys, Lotte; Bauters, Dries; Roose, Elien; Tersteeg, Claudia; Vanhoorelbeke, Karen; Hoylaerts, Marc F.; Lijnen, Roger H.; Scroyen, Ilse: ADAMTS13 deficiency promotes microthrombosis in a murine model of diet-induced liver steatosis
27
Sandén, Per; Renlund, Henrik; Svensson, Peter J.; Själander, Anders: Bleeding complications and mortality in warfarin-treated VTE patients, dependence of INR variability and iTTR
33
Biswas, Moanaro; Rogers, Geoffrey L.; Sherman, Alexandra; Byrne, Barry J.; Markusic, David M.; Jiang, Haiyan; Herzog, Roland W.: Combination therapy for inhibitor reversal in haemophilia A using monoclonal anti-CD20 and rapamycin
Zusatzmaterial
44
Zhao, Bing; Zhang, Yanling; Huang, Yinong; Yu, Jinchao; Li, Yaran; Wang, Qi; Ma, Yixin; Song, Hou-Yan; Yu, Min; Mo, Wei: A novel hirudin derivative inhibiting thrombin without bleeding for subcutaneous injection
Zusatzmaterial
57
Cohen, Alexander T.; Katholing, Anja; Rietbrock, Stephan; Bamber, Luke; Martinez, Carlos: Epidemiology of first and recurrent venous thromboembolism in patients with active cancer
Zusatzmaterial
66
Bastida, Jose Maria; González-Porras, Jose Ramon; Jiménez, Cristina; Benito, Rocio; Ordoñez, Gonzalo R.; Álvarez-Román, Maria Teresa; Fontecha, M. Elena; Janusz, Kamila; Castillo, David; Fisac, Rosa Maria; García-Frade, Luis Javier; Aguilar, Carlos; Martínez, Paz Maria; Bermejo, Nuria; Herrero, Sonia; Balanzategui, Ana; Martin-Antorán, Jose Manuel; Ramos, Rafael; Cebeiro, Maria Jose; Pardal, Emilia; Aguilera, Carmen; Pérez-Gutierrez, Belen; Prieto, Manuel; Riesco, Susana; Mendoza, Maria Carmen; Benito, Ana; Benito-Sendin, Ana Hortal; Jimenez-Yuste, Victor; Hernández-Rivas, Jesus Maria; García-Sanz, Ramon; González-Díaz, Marcos; Sarasquete, Maria Eugenia: Application of a molecular diagnostic algorithm for haemophilia A and B using next-generation sequencing of entire F8, F9 and VWF genes
Zusatzmaterial
75
Ågren, Anna; Holmström, Margareta; Schmidt, David E.; Hosokawa, Kazuya; Blombäck, Margareta; Hjemdahl, Paul: Monitoring of coagulation factor therapy in patients with von Willebrand disease type 3 using a microchip flow chamber system
83
Breitenstein, Alexander; Stämpfli, Simon F.; Reiner, Martin F.; Shi, Yi; Keller, Stephan; Akhmedov, Alexander; Clerigué, Ariane Schaub; Spescha, Remo D.; Beer, Hans-Jürg; Lüscher, Thomas F.; Tanner, Felix C.; Camici, Giovanni G.: The MAP kinase JNK2 mediates cigarette smoke-induced arterial thrombosis

Cellular Haemostasis and Platelets

90
Riedl, Julia; Kaider, Alexandra; Marosi, Christine; Prager, Gerald W.; Eichelberger, Beate; Assinger, Alice; Pabinger, Ingrid; Panzer, Simon; Ay, Cihan: Decreased platelet reactivity in patients with cancer is associated with high risk of venous thromboembolism and poor prognosis
Zusatzmaterial
99
Flierl, Ulrike; Zauner, Florian; Sieweke, Jan-Thorben; Berliner, Christine; Napp, L. Christian; Tillmanns, Jochen; Bauersachs, Johann; Schäfer, Andreas: Efficacy of prasugrel administration immediately after percutaneous coronary intervention in ST-elevation myocardial infarction
105
Schaletzki, Yvonne; Kromrey, Marie-Luise; Bröderdorf, Susanne; Hammer, Elke; Grube, Markus; Hagen, Paul; Sucic, Sonja; Freissmuth, Michael; Völker, Uwe; Greinacher, Andreas; Rauch, Bernhard H.; Kroemer, Heyo K.; Jedlitschky, Gabriele: Several adaptor proteins promote intracellular localisation of the transporter MRP4/ABCC4 in platelets and haematopoietic cells
Zusatzmaterial
116
Lorthongpanich, Chanchao; Jiamvoraphong, Nittaya; Supraditaporn, Kantpitchar; Klaihmon, Phatchanat; U-pratya, Yaowalak; Issaragrisil, Surapol: The Hippo pathway regulates human megakaryocytic differentiation
Zusatzmaterial

New Technologies, Diagnostic Tools and Drugs

127
Maeda, Takuma; Nakagawa, Katsura; Murata, Kuniko; Kanaumi, Yoshiaki; Seguchi, Shu; Kawamura, Shiori; Kodama, Mayumi; Kawai, Takeshi; Kakutani, Isami; Ohnishi, Yoshihiko; Kokame, Koichi; Okazaki, Hitoshi; Miyata, Shigeki: Identifying patients at high risk of heparin-induced thrombocytopenia-associated thrombosis with a platelet activation assay using flow cytometry
Zusatzmaterial

Stroke, Systemic or Venous Thromboembolism

139
Ambrosino, Pasquale; Tarantino, Luciano; Di Minno, Giovanni; Paternoster, Mariano; Graziano, Vincenzo; Petitto, Maurizio; Nasto, Aurelio; Di Minno, Matteo Nicola Dario: The risk of venous thromboembolism in patients with cirrhosis
149
Zhang, Lili; Segal, Alan Z.; Leifer, Dana; Silverstein, Roy L.; Gerber, Linda M.; Devereux, Richard B.; Kizer, Jorge R.: Circulating protein Z concentration, PROZ variants, and unexplained cerebral infarction in young and middle-aged adults
158
Leung, Raymond Y. H.; Han, Yi; Sing, Chor-Wing; Cheung, Bernard M. Y.; Wong, Ian C. K.; Tan, Kathryn C. B.; Kung, Annie W. C.; Cheung, Ching-Lung: Serum 25-hydroxyvitamin D and the risk of stroke in Hong Kong Chinese
Zusatzmaterial

Atherosclerosis and Ischaemic Disease

164
Winkels, Holger; Meiler, Svenja; Smeets, Esther; Lievens, Dirk; Engel, David; Spitz, Charlotte; Bürger, Christina; Rinne, Petteri; Beckers, Linda; Dandl, Angelika; Reim, Sigrid; Ahmadsei, Maiwand; Van den Bossche, Jan; Holdt, Lesca M.; Megens, Remco T. A.; Schmitt, Martin M.; de Winther, Menno; Biessen, Eric A.; Borst, Jannie; Faussner, Alexander; Weber, Christian; Lutgens, Esther; Gerdes, Norbert: CD70 limits atherosclerosis and promotes macrophage function
Zusatzmaterial
176
Vorlova, Sandra; Koch, Miriam; Manthey, Helga D.; Cochain, Clement; Busch, Martin; Chaudhari, Sweena M.; Stegner, David; Yepes, Manuel; Lorenz, Kristina; Nolte, Marc W.; Nieswandt, Bernhard; Zernecke, Alma: Coagulation factor XII induces pro-inflammatory cytokine responses in macrophages and promotes atherosclerosis in mice
Zusatzmaterial

Trial Protocol Design Paper

188
Sibbing, Dirk; Aradi, Dániel; Jacobshagen, Claudius; Gross, Lisa; Trenk, Dietmar; Geisler, Tobias; Orban, Martin; Gori, Tommaso; Hadamitzky, Martin; Merkely, Béla; Kiss, Róbert Gábor; Komócsi, András; Dézsi, Csaba A.; Thalmeier, Andreas; Löw, Anja; Holdt, Lesca; Teupser, Daniel; Ince, Hüseyin; Felix, Stephan B.; Parma, Radoslaw; Malek, Lukasz; Horstkotte, Jan; Baylacher, Monika; Schwinger, Robert; Rieber, Johannes; Mudra, Harald; Hausleiter, Jörg; Huber, Kurt; Neumann, Franz-Josef; Koltowski, Lukasz; Huczek, Zenon; Mehilli, Julinda; Massberg, Steffen; on behalf of the TROPICAL-ACS Investigators: A randomised trial on platelet function-guided de-escalation of antiplatelet treatment in ACS patients undergoing PCI
Zusatzmaterial

Letters to the Editor

196
Quintard, Hervé; Viard, Delphine; Drici, Milou-Daniel; Ruetsch, Caroline; Samama, Charles Marc; Ichai, Carole: Idarucizumab administration for reversing dabigatran effect in an acute kidney injured patient with bleeding
198
Ridsdale, Sallyann; Martin, Victoria; Payne, Jeanette H.: Capillary blood samples for anti-Xa monitoring of heparin in paediatric patients
201
Engwenyu, Lydia R.; Franchi, Francesco; Rollini, Fabiana; Cho, Jung Rae; DeGroat, Christopher; Bhatti, Mona; Alobaidi, Zeina; Ferrante, Elisabetta; Jakubowski, Joseph A.; Sugidachi, Atsuhiro; Zenni, Martin M.; Bass, Theodore A.; Angiolillo, Dominick J.: Impact of chronic kidney disease on platelet P2Y12 receptor signalling in patients with type 2 diabetes mellitus
Zusatzmaterial

Editors’ Choice

204
Weber, Christian; Lip, Gregory Y. H.: Editors’ Choice 2016 papers in Thrombosis and Haemostasis