DOI: 10.1055/s-00000131

Synfacts

Issue 07 · Volume 14 · July 2018 DOI: 10.1055/s-008-40793

Synform

A102
Zanda, Matteo: SYNFORM ISSUE 2018/07

Synthesis of Natural Products and Potential Drugs

z0663
All PDFs of this category
0663
Divergent Approach to Enmein-Type Natural Products
0664
Synthesis of Marbostat-100
0665
Synthesis of Fosdevirine
0666
Synthesis of (±)-Cephanolide B and C
0667
Synthesis of (+)-Hinckdentine A
0668
Synthesis of an MK2 Inhibitor
0669
Synthesis of Pibrentasvir
0670
Synthesis of MK-8282
0671
Synthesis of (±)-Incargranine A
0672
Total Synthesis of (+)-Cyclocitrinol
0673
Synthesis of (±)-Azitine
0674
Synthesis of Ivosidenib
0675
Synthesis of PF-06869206
0676
Total Synthesis of (±)-Acremoxanthone A

Synthesis of Heterocycles

z0677
All PDFs of this category
0677
Dihydrobenzofuran Synthesis by Palladium/Norbornene Cooperative Catalysis
0678
Copper-Catalyzed Three-Component Synthesis of Thiazoles
0679
Synthesis of 2-Substituted Indolines via Allyl Boronic Acids Generated in situ
0680
Dioxines and Oxathiines from Epoxides and Episulfides
0681
Gram-Scale Synthesis of Cyclobutane-Fused Pyrrolidines and Piperidines
0682
Regioselective Synthesis of 3-Halopyrazoles
0683
Synthesis of Azolopyrimidines through Rhodium-Catalyzed C–H Functionalization
0684
Flipping a Switch to Access Aziridines
0685
One-Pot Synthesis of Fluoroindenones
0686
Nickel-Mediated C(sp2)–H Amination: Synthesis of Anthranilic Amides
0687
Preparation of Quinazolines from Alkynes and 2-Aryldihydrophthalazinediones
0688
Copper-Catalyzed Synthesis of 5-Arylindazolo[3,2-b]quinazolinones
0689
Synthesis of Imidazolidin-5-ones from Azlactones and β-Carbolines
0690
Copper-Catalyzed Synthesis of Azole-Fused Quinazolines
0691
Synthesis of 2-Aroylbenzofurans from Arynes and Sulfur Ylides

Synthesis of Materials and Unnatural Products

z0693
All PDFs of this category
0693
Nanoporous Graphene from a Carefully Designed Molecular Precursor
0694
Heteroatom-Coordinated Conducting Polymers
0695
Buckle Up: It’s the Lawesson’s Reagent Derived Macrocycles
0696
Economical Synthesis of Heteroaromatic Compounds with Reusable Catalysts
0697
Flipping the Switch on Controlled Polymerization
0698
syn-Tribenzotriquinacene Dimers Make Edges for a Molecular Cube
0699
Supramolecular Polymers with a Zwitterionic Backbone
0700
Metallophilic Phosphorescence Polymers
0701
Cyclic 1,8-Diphenylanthracene Dimer
0702
Planar Cyclic Oligothienoacenes for Field-Effect Transistors
0703
Cycloaddition Affords Two Helicenes for the Price of One
0704
Intramolecular Locked Chiral Terpyridine Complexes

Metal-Catalyzed Asymmetric Synthesis and Stereoselective Reactions

z0705
All PDFs of this category
0705
Enantioselective Radical Addition to Heteroarenes
0706
Ruthenium-Catalyzed Diastereoselective Synthesis of Hydronaphthylamines
0707
Enantioselective Dearomatization of Pyridines with Styrene-Derived Nucleophiles
0708
Ruthenium-Catalyzed Asymmetric Addition of Trifluoromethylcarbene to Olefins
0709
Rhodium-Catalyzed Enantioselective Synthesis of C2-Symmetric Macrodiolides
0710
Copper-Catalyzed Double Proto-Silylations of Electron-Deficient Enynes
0711
Pd-Catalyzed Enantioselective Synthesis of Quaternary C–F Oxindoles
0712
Palladium-Catalyzed Enantioselective Birch–Heck Sequence Reaction
0713
Kinetic Resolution in Copper-Catalyzed 1,3-Dipolar Cycloadditions
0714
Rhodium-Catalyzed Asymmetric Hydroborylation of γ,δ-Unsaturated Amides
0715
Palladium-Catalyzed Asymmetric γ-C(sp3)–H Activation of Alkyl Amines
0716
Enantioselective Copper-Catalyzed Dearomative Bromination
0717
C(sp)–H Addition of Terminal Alkynes to Cyclo-propenes by a Chiral Gadolinium Catalyst
0718
Enantioselective α-Allylation of Aldehydes with Alkynes
0719
Pd-Catalyzed Enantioselective Synthesis of 4-Vinylimidazolidin-2-ones
0720
Gold(I)-Catalyzed Regio- and Stereospecific Oxycyclization: Synthesis of Indenes
0721
Cu-Catalyzed Asymmetric 1,4-Addition of Alkylzirconocenes to Dienones or Ynenones
0722
Rhodium-Catalyzed Enantioselective Synthesis of Dihydroisoquinolones
0723
Tetracyclic Indolines with Four Continuous Stereocenters via AMCRs
0724
Ni–Al Bimetallic Catalyzed Enantioselective C–H Cyclization
0725
Rhodium-Catalyzed C–H Functionalization of Silicon-Substituted Alkanes
0726
Cooperative Catalyzed, Decarboxylative Propargylation/Hydroamination
0727
Ruthenium-Catalyzed Stereoselective C–H Allylation of Indoles
0728
Cooperative Boron–Palladium Catalysis for Asymmetric Allylation
0729
Enantioselective Iridium-Catalyzed Nazarov Cyclization
0730
Pd/Zn-Catalyzed Asymmetric Transfer Hydrogenation of Imines with Alcohols
0731
Copper-Catalyzed 1,4-Addition and Subsequent SCF3 Trap
0732
Dynamic Kinetic Resolution−Asymmetric Transfer Hydrogenation
0733
Cobalt-Catalyzed Enantioselective Radical Cyclization of Diazo Compounds
0734
Asymmetric Synthesis of Allenyl Boronates

Metal-Mediated Synthesis

z0735
All PDFs of this category
0735
Nickel- or Palladium-Catalyzed Cross-Coupling Polycondensation
0736
11C–C Bond Formation via Negishi Cross-Coupling
0737
Magnesium Ethoxide Mediated Synthesis of Amidines
0738
Synthesis of Salicylidene Urea Derivatives by Snieckus–Fries-Type Rearrangement
0739
Chemoselective Approach Towards α-Aryl and -Alkyl Selenomethylketones
0740
Solid-State Enantioselective Arylation of Aldehydes in Batch and Continuous-Flow
0741
Metal Acetylide Elimination during the Transformation of Propargyl Amines
0742
Radical C–H Trifluoromethylation of Peptides
0743
Palladium-Catalyzed C–H Arylation
0744
Petasis Allylation Reaction Enabled by Hydroxyl Groups
0745
Intramolecular Alkylboration of Terminal Allenes
0746
Cobalt-Catalyzed Borylation of Aryl Halides
0747
Generation of Grignard Reagents in Toluene
0748
Asymmetric Synthesis of β-Functionalized Ketones over an Immobilized Rh Catalyst
0749
Oxidative Trifluoromethylthioarylation of Styrenes Using Aryldiazonium Salts

Organo- and Biocatalysis

z0751
All PDFs of this category
0751
Bis(guanidino)iminophosphorane-Catalyzed Mannich-Type Reaction
0752
Helically Chiral Anions for Inverse-Electron-Demand Diels–Alder Reactions
0753
Cooperative Catalysis: Radical Addition to Olefins and Asymmetric Protonation
0754
Stereodivergent Cyclopropanation of Nonactivated Alkenes
0755
Enzymatic Synthesis of Highly Strained Carbocycles
0756
Chiral Phosphoric Acid Catalyst for Desymmetrization of meso-Diones
0757
Asymmetric Brønsted Acid Catalysts for Activation of Olefins
0758
Ammonium Salt Catalyzed Monohalogenation of Phenols
0759
Lewis Base Catalyzed Asymmetric Polyene Sulfenocyclization
0760
Chiral-Acid-Catalyzed Asymmetric Dehydrative 4π Electrocyclization

Polymer-Supported Synthesis

z0761
All PDFs of this category
0761
Continuous-Flow Pd/C-Catalyzed Reductive Alkylation of Alcohols with Aldehydes
0762
Copper(I) Oxide Catalyzed Dealkylation of Alkyl Aryl Ethers
0763
Copper-Catalyzed Preparation of Sulfides and Disulfides
0764
Recyclable Catalyst for Electrochemical Thiocyanation and Sulfenylation
0765
Carbon Nanotube Supported Copper Ferrite Catalyst for Huisgen Cycloaddition
0766
Silylation of Aryl Halides with Hydrosilanes Using Pd–Pt–Fe3O4
0767
Sequential Nitro Reduction and Reductive Amination on AuPd–Fe3O4
0768
CuI Nanoparticle Catalyzed Cross-Coupling of Alkynes with Amines
0769
Palladium Nanoparticle Catalyzed Synthesis of Indanones
0770
Palladium Nanocluster Catalyzed Larock Indole Synthesis
0771
Hydrogenation of Phenol Derivatives on a Palladium Nanocatalyst
0772
Direct 2-Alkylation of Azoles with Ethers on Zeolite-Supported Cobalt
0773
Synthesis of Triazoles and Propargylamines on a Supported Copper–Schiff Base
0774
Synthesis of Aminonaphthoquinones on Graphene Oxide Immobilized Cu(II)