Synfacts
Ausgabe 04 · April 2019
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Ausgabe
Synform
A48
Zanda, Matteo:
SYNFORM
ISSUE 2019/04
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Synthesis of Natural Products and Potential Drugs
z0333
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PDF (518 kb)
0333
Synthesis of an HIV-1 Integrase Allosteric Site Inhibitor
FREIER ZUGRIFF
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PDF (147 kb)
0334
Synthesis of Paspaline A and Emindole PB
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PDF (88 kb)
0335
Synthesis of Eburnane-Type Alkaloids
FREIER ZUGRIFF
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PDF (148 kb)
0336
Synthesis of (+)-Dysoline
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PDF (89 kb)
0337
Synthesis of Atuveciclib
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PDF (86 kb)
0338
Synthesis of a Glucokinase Activator
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PDF (88 kb)
0339
Synthesis of Gefitinib
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PDF (69 kb)
0340
Asymmetric Total Synthesis of (+)-Laurallene
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PDF (88 kb)
0341
Asymmetric Synthesis of Netarsudil
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PDF (95 kb)
0342
Synthesis of 2′-Fluoro-6′-methylene-carbocyclic Adenosine (FMCA)
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PDF (100 kb)
0343
Syntheses of Δ
12
-Prostaglandin J Natural Products
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PDF (102 kb)
0344
Synthesis of LX2761
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PDF (81 kb)
0345
Synthesis of (+)-Pleurocins A and B
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PDF (100 kb)
0346
Synthesis of (±)-Estrone
FREIER ZUGRIFF
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PDF (138 kb)
Synthesis of Heterocycles
z0347
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PDF (352 kb)
0347
Three-Component Synthesis of Quinazolinones
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PDF (82 kb)
0348
New Biocatalytic Synthesis of Caprolactone by Oxidative Lactonization
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PDF (80 kb)
0349
Organocatalytic Synthesis of Enantioenriched Five- and Six-Membered Cyclic Ureas
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PDF (91 kb)
0350
Synthesis of Indolo[1,2-α]indole Derivatives by Gold(I)-Catalyzed Cycloisomerization
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PDF (95 kb)
0351
Gold Carbene Route to Several Classes of Azaheterocycles
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PDF (82 kb)
0352
Photodecarboxylative Azidation of Cyclic Amino Acids with Rhodamine 6G
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PDF (81 kb)
0353
Palladium(II)-Catalyzed Activation for Nucleophilic Substitution Reactions
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PDF (80 kb)
0354
Cobalt-Catalyzed Synthesis of Quinolines and Acridines from Anthranils
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PDF (89 kb)
0355
Spiroindolines by Visible-Light-Mediated Intramolecular Cycloadditions
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PDF (89 kb)
0356
Synthesis of Pyrrolophenanthridine Alkaloids by the Schmidt Reaction
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PDF (90 kb)
0357
Synthesis of 2-Aminopyrroles and Quinoline-Based Polyazaheterocycles
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PDF (92 kb)
0358
Titanocene-Catalyzed Synthesis of Functionalized Ring-Fused Piperidines
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PDF (89 kb)
0359
Electrochemical Synthesis of Fluorinated 2-Oxazolines
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PDF (73 kb)
0360
Synthesis of Carbazoles and Indolines by Gold-Catalyzed Diels–Alder Reactions
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PDF (85 kb)
0361
Synthesis of (5
E
)-5-(Iodomethylene)-1,3-selenazolidin-2-ones
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PDF (88 kb)
Synthesis of Materials and Unnatural Products
z0363
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0363
A New Twist on Sydnones
FREIER ZUGRIFF
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PDF (127 kb)
0364
A Mechanically Stabilized Helical Chiral Macrocycle
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PDF (92 kb)
0365
Thiophenes through Thiolates
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PDF (70 kb)
0366
Copper-Catalyzed Oxidation of Siloxanes to Polar Siloxanes
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PDF (75 kb)
0367
Open and Shut Synthesis of an Oligoparaphenylene Dual Nanohoop
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PDF (75 kb)
0368
Stars Align for Liquid Crystals via a New Supramolecular Click Mechanism
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PDF (92 kb)
0369
Mind the Gap: Finite Nanotubes with Periodic Wall Defects
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PDF (81 kb)
0370
A Rare Example of a Retro Baeyer–Villiger Reaction
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PDF (92 kb)
0371
Spontaneous CO
2
Conversion into Polymeric Materials
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PDF (72 kb)
0372
Loose Canon: Tunable Quiniodal Macrocycles with Canonical and Zwitterionic Ground States
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PDF (74 kb)
0373
Copper-Mediated Homocoupling for Naphthotetraindole Synthesis
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PDF (73 kb)
0374
Everybody Loves Pie: Nitrogen-Doped Pyrenes
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PDF (83 kb)
Metals in Synthesis
z0375
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0375
Cyclohexane Desymmetrization via Rhodium-Catalyzed C–H Activation
FREIER ZUGRIFF
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PDF (118 kb)
0376
Iron(III)-Catalyzed Carbonyl-Olefin Metathesis of Aliphatic Ketones
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PDF (71 kb)
0377
Enantioselective Arylative Trifluoromethylation of Alkenes
FREIER ZUGRIFF
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PDF (127 kb)
0378
Bimetallic Hydroaminomethylation of α-Olefins
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PDF (91 kb)
0379
Nickel-Catalyzed Alkylation of Heterocycles
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PDF (72 kb)
0380
Cross-Dehydrogenative Heteroarylation of Cyclic Amines
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PDF (80 kb)
0381
Asymmetric C(sp
3
)–H Arylation Through a Hybrid Palladium Catalyst
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PDF (79 kb)
0382
Asymmetric C(sp
3
)–H Amidation of Thioamides Catal-yzed by a Cobalt
III
/Chiral Carboxylic Acid Hybrid System
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PDF (77 kb)
0383
Diastereoselective Formation of All-
cis
-(Multi)Fluorinated Piperidines
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PDF (75 kb)
0384
Iron(II)-Catalyzed Alkyl Heck Coupling
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PDF (76 kb)
0385
Enantioselective Iron-Catalyzed Couplings of Aldehydes and Alkenes
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PDF (70 kb)
0386
Cobalt(III)-Catalyzed [4+2] Annulation
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PDF (77 kb)
0387
Cobalt-Catalyzed [2+2] Cycloaddition
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PDF (72 kb)
0388
Chromium-Catalyzed Asymmetric Allylation
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PDF (75 kb)
0389
Synthesis of Fully Substituted Cyclopentenones
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PDF (77 kb)
0390
Rhodium-Catalyzed Enantioselective Cyclopropanations
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PDF (73 kb)
0391
Sequential
meta
-C–H/
ipso
-C–O Functionalization of Phenols via Directing-Group Strategy
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PDF (90 kb)
0392
Copper-Catalyzed Remote Trifluoromethylation
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PDF (76 kb)
0393
A New Late-Stage Defluorosilylation
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PDF (74 kb)
0394
Catellani Reaction: Synthesis of
o
,
o
′-Disubstituted Vinylarenes
FREIER ZUGRIFF
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PDF (138 kb)
0395
Copper-Catalyzed Enantioselective Reduction of α,β-Unsaturated Esters
FREIER ZUGRIFF
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PDF (133 kb)
0396
Iridium-Catalyzed Three-Component Coupling Reaction
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PDF (71 kb)
0397
Palladium-Catalyzed Dearomative Intermolecular [4+1] Spiroannulation by C(sp
3
)–H Activation
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PDF (77 kb)
0398
Iridium-Catalyzed Asymmetric Allylic O-Alkylation of Ketones
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PDF (77 kb)
0399
Iron-Catalyzed Carbon (sp
2
)–Carbon (sp
2
) Oxidative Homo-Coupling
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HTML
PDF (69 kb)
0400
Molybdenum-Catalyzed Direct Amination of Boronic Acids
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PDF (71 kb)
0401
Stereoselective Synthesis of
anti
-Isomers of γ-Boryl-Substituted Homoallylic Alcohols
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PDF (92 kb)
0402
Enantioselective Aryl Transfer using Chiral Lithium Amido Aryl Zincates
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PDF (76 kb)
0403
Dual Photoredox/Copper Catalysis for C–H Functionalizations
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PDF (85 kb)
0404
Gold-Catalyzed Temperature-Controlled Divergent Hydroamination/Cycloaddition Cascade Reactions
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PDF (81 kb)
Polymer-Supported Synthesis
z0405
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PDF (427 kb)
0405
Hydroamination of Terminal Alkynes on Gold Nanoclusters
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PDF (82 kb)
0406
Selective Catalytic Hydrogenation of α,β-Unsaturated Aldehydes
FREIER ZUGRIFF
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PDF (94 kb)
0407
Oxidation of Alcohols on Thermoresponsive-Polymer-Supported TEMPO
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PDF (125 kb)
0408
A
3
Coupling Reactions on Green-Synthesized Gold Nanoparticles
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PDF (86 kb)
0409
Palladium-Catalyzed Carbocyclization–Borylation of Enallenols
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PDF (94 kb)
0410
Tandem Catalytic C–H Arylation/Suzuki–Miyaura Coupling
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PDF (80 kb)
0411
Photocatalytic Coupling Reactions on a Mixed-Ligand Metal–Organic Framework
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PDF (78 kb)
0412
Knoevenagel–Michael and Click Reactions on a Cu(II)/Natural Phosphate Catalyst
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PDF (80 kb)
0413
Pd(II)-Complex-Catalyzed Mizoroki–Heck Reaction in γ-Valerolactone
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PDF (151 kb)
0414
Synthesis of Pyranopyrazoles Using TiO
2
-Coated Fe
3
O
4
-Immobilized Tungstic Acid
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PDF (88 kb)
0415
Palladium-Photocatalyzed Self-Condensation of Primary Amines
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PDF (83 kb)
0416
Synthesis of 4
H
-Pyrimido[2,1-
b
]benzothiazoles with a Heterogeneous Cu(II) Catalyst
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PDF (101 kb)
0417
Denitrative Cyclizations of β-Nitrostyrenes on Supported Pd Nanoparticles
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PDF (85 kb)
0418
Synthesis of Benzimidazoles Promoted by Rh@PS
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PDF (81 kb)
Organo- and Biocatalysis
z0419
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PDF (562 kb)
0419
Application of Chemoinformatics in Asymmetric Catalysis
FREIER ZUGRIFF
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PDF (148 kb)
0420
Asymmetric Enzymatic Aminohydroxylation of Styrenyl Olefins
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PDF (90 kb)
0421
Directed Evolution Permits Heme-Protein-Catalyzed sp
3
-C–H Alkylation
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PDF (227 kb)
0422
Asymmetric Synthesis of Trifluoromethylated Spirooxindole Lactones
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PDF (86 kb)
0423
Asymmetric Synthesis of All-Carbon Spirocycles by a Stetter/Aldol Cascade
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PDF (85 kb)
0424
Chiral Bifunctional Phase-Transfer Catalysts for Asymmetric Aminations
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PDF (87 kb)
0425
Electrophilic Sulfenylation of Indoles by P
III
/P
V
=O Catalysis
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PDF (74 kb)
0426
NHC-Catalyzed Aza-Stetter Reaction of Aldimines To Give 3-Methylenechromanones
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PDF (89 kb)
0427
Aminoxyl-Catalyzed Electrochemical Diazidation of Alkenes
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PDF (75 kb)
0428
The Knoevenagel Condensation
FREIER ZUGRIFF
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PDF (144 kb)
Chemistry in Medicine and Biology
z0429
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PDF (477 kb)
0429
A Chemoselective Conjugation of Peptides with Electron-Rich (Hetero)Arenes
FREIER ZUGRIFF
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PDF (129 kb)
0430
Specific Functionalization of Cysteine and Lysine Using Dinitroimidazoles
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PDF (84 kb)
0431
Late-Stage Functionalization of Complex Primary Sulfonamides via NHC Catalysis
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PDF (80 kb)
0432
Application of Hemithioindigo Photoswitches in Photopharmacology
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PDF (81 kb)
0433
Synthesis of Aglaroxin C Analogues for Hepatitis C Viral Infection Inhibition
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PDF (88 kb)
0434
Synthesis of a cGAMP Analogue
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PDF (83 kb)
0435
A Small Clickable and Photoconvertible Fluorophore
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PDF (90 kb)
0436
Synthesis of AWZ1066S, an anti-Wolbachia Drug Candidate
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PDF (80 kb)
0437
Pyrazolopyrimidines: Molecular Correctors for MALT1-Related Immune Defects
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PDF (90 kb)
0438
Selective Targeting of p38 MAPK Isoforms Using PROTACs
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PDF (92 kb)
0439
Synthesis of Human Interleukin-8 by Native Chemical Ligation
FREIER ZUGRIFF
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PDF (127 kb)
0440
Synthesis of a Fluorescent Probe for Cell Surface Phosphatidylserine
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HTML
PDF (81 kb)
0441
Synthesis of ‘Stretched’ Isosteres of Saturated Nitrogen Heterocycles
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PDF (80 kb)
0442
Targeting Zinc Homeostasis in Cancer
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PDF (81 kb)
0443
A Glutathione-Labile Oligonucleotide Protecting Group
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PDF (71 kb)
Peptide Chemistry
z0445
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Volltext
PDF (387 kb)
0445
O-Glycosylation of Unprotected Peptides
FREIER ZUGRIFF
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HTML
PDF (119 kb)
0446
One-Pot Peptide Modifications Using the MeDbz Linker
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HTML
PDF (78 kb)
0447
Synthesis of Free α-Amino Acids from 1,2-Diols
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HTML
PDF (95 kb)
0448
Two-Step Strategy for Thioamide Bond Formation by Using an Ynamide
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HTML
PDF (79 kb)
0449
Photoredox-Catalyzed α-Fluoro
-
α-Amino Acid Synthesis
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HTML
PDF (93 kb)
0450
Photoredox Catalysis with Amino Acid- and Peptide-Derived Katritzky Salts
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PDF (73 kb)
0451
Petasis Reaction for Late-Stage Functionalization of Peptides
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PDF (88 kb)
0452
Photocatalytic Decarboxylative C(sp
3
)–H Alkylation of Glycine or Peptides
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HTML
PDF (73 kb)
0453
Manganese-Catalyzed Synthesis of Acylic, Hybrid, and Stapled Peptides
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PDF (76 kb)
0454
Palladium-Catalyzed Asymmetric Aminomethylation
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PDF (93 kb)
0455
Total Chemical Synthesis of a Glycoprotein by Native Chemical Ligation
FREIER ZUGRIFF
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PDF (150 kb)
Flow Chemistry
z0457
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Volltext
PDF (158 kb)
0457
Automated Titration of Organometallic Reagents in Continuous Flow
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PDF (79 kb)
0458
Oxidation of Csp
3
–H Bonds in Flow Using Methyl(trifluoromethyl)dioxirane
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HTML
PDF (80 kb)
0459
Continuous-Flow Chemoenzymatic Dynamic Kinetic Resolution of Amines
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PDF (131 kb)
0460
Continuous-Flow Diazotization
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PDF (71 kb)
Erratum
0461
Gong, T.-J; Hea, S.-J; Lu, X; Pi, J.-J; Fu, Y; Wang, X.-X:
Defluorinative Alkylation using Redox-Active Esters
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PDF (61 kb)
0461
Seidl, F J; Min, C; Lopez, J A; Burns, N Z:
Regio- and Enantioselective Haloazidation of Allylic Alcohols
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PDF (62 kb)
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