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Synfacts 2009(9): 1019-1019  
DOI: 10.1055/s-0029-1217690
Metal-Mediated Synthesis
© Georg Thieme Verlag Stuttgart ˙ New York

Copper(I)-Catalyzed Room-Temperature Borylation of Aryl Halides

Contributor(s): Paul Knochel, Andrei Gavryushin
C. Kleeberg, L. Dang, Z. Lin*, T. B. Marder*
Durham University, UK and The Hong Kong University of Science and Technology, Kowloon, Hong Kong
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Publication History

Publication Date:
21 August 2009 (online)

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Significance

Arylboronic derivatives are of great importance in modern organic synthesis. This direct conversion of aryl halides into boronic esters is a simple and convenient method allowing an easy preparation of a variety of pinacol boronates. It utilizes an inexpensive CuBr/n-Bu3P catalytic system which is efficient even for electron-rich aryl bromides.