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Synfacts 2009(9): 1028-1028  
DOI: 10.1055/s-0029-1217763
Metal-Mediated Synthesis
© Georg Thieme Verlag Stuttgart ˙ New York

Gold-Catalyzed Synthesis of Piperidin-4-ones

Contributor(s): Paul Knochel, Tobias Thaler
L. Cui, Y. Peng, L. Zhang*
University of Nevada, Reno, USA
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Publikationsverlauf

Publikationsdatum:
21. August 2009 (online)

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Significance

An efficient method for the direct synthesis of piperidin-4-ones using gold catalysis has been developed. This gold-catalyzed protocol benefits from its compatibility with basic amines which are known to coordinate and poison rhodium catalysts.