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Synfacts 2010(2): 0245-0245
DOI: 10.1055/s-0029-1219055
DOI: 10.1055/s-0029-1219055
Polymer-Supported Synthesis
© Georg Thieme Verlag
Stuttgart ˙ New York
Direct Reductive Amination with Gum Acacia Stabilized Pd Nanoparticles
B. Sreedhar*, P. S. Reddy, D. K. Devi
Indian Institute of Chemical Technology, Hyderabad, India
Further Information
Publication History
Publication Date:
21 January 2010 (online)
![](https://www.thieme-connect.de/media/synfacts/201002/lookinside/thumbnails/10.1055-s-0029-1219055-1.jpg)
Significance
Gum acacia stabilized palladium nanoparticles (GA-Pd nanoparticles) were prepared and applied to a reductive amination reaction. The GA-Pd nanoparticles catalyzed the direct one-pot reductive amination of aldehydes 2 with nitroarenes 1 under atmospheric pressure of hydrogen to give the corresponding amines 3 in up to 96% yield (eq. 2, 18 examples).