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Synfacts 2010(5): 0537-0537
DOI: 10.1055/s-0029-1219683
DOI: 10.1055/s-0029-1219683
Synthesis of Materials and Unnatural Products
© Georg Thieme Verlag
Stuttgart ˙ New York
1,2-Diborylation of Arynes
H. Yoshida*, K. Okada, S. Kawashima, K. Tanino, J. Ohshita
Hiroshima University, Japan
Further Information
Publication History
Publication Date:
22 April 2010 (online)
![](https://www.thieme-connect.de/media/synfacts/201005/lookinside/thumbnails/10.1055-s-0029-1219683-1.jpg)
Significance
The authors report a platinum isocyanide complex catalyzed method for the diborylation of arynes. Utilizing this optimized catalyst, the authors can efficiently prepare a variety of 1,2-diborylarenes from readily available bis(pinacolato)diboron and silyl triflate aryne precursors. The synthetic utility of these products was demonstrated through several different Suzuki-Miyaura cross-coupling reactions. Both symmetrical, double cross-couplings, and tandem double, unsymmetrical cross-couplings occur in good yields. Additionally, it is possible to produce the mono cross-coupled product.