General Methodology for the α-Alkylation of Cyclic Ketones

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Synfacts 2024; 20(09): 0915
DOI: 10.1055/s-0043-1775049

Synthesis of Heterocycles

Contributor(s):

Paul Richardson (Pfizer)

α-alkylation - Grignard reagents - organocopper - hydrogenation - piperidines - pyrrolidines - late-stage functionalization

Article published online:
16 August 2024

Georg Thieme Verlag KG
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