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Synlett 2010(18): 2781-2783
DOI: 10.1055/s-0030-1258819
DOI: 10.1055/s-0030-1258819
LETTER
© Georg Thieme Verlag
Stuttgart ˙ New York
Condensed Oxaziridine-Mediated [3+2] Cycloaddition: Synthesis of Polyhetero-bicyclo Compounds
Further Information
Publication History
Received
19 July 2010
Publication Date:
08 October 2010 (online)


Abstract
Polyhetero-bicyclo compounds were synthesized by a regioselective [3+2]-cycloaddition reaction between stable condensed oxaziridines and alkenes, alkynes, and nitriles. These molecules showed considerable antimicrobial activity against several gram-positive bacteria.
Key words
condensed oxaziridines - polyhetero-bicyclo - regioselectivity - [3+2] cycloaddition - bactericidal properties
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