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Synfacts 2009(8): 0900-0900
DOI: 10.1055/s-0029-1217487
DOI: 10.1055/s-0029-1217487
Metal-Mediated Synthesis
© Georg Thieme Verlag
Stuttgart ˙ New York
Indium-Mediated Butadienylation of Imines
D. Seomoon, J. A, P. H. Lee*
Kangwon National University, Chuncheon, Republic of Korea
Further Information
Publication History
Publication Date:
23 July 2009 (online)
Significance
A novel straightforward and general method for the 1,3-butadien-2-ylation of imines is presented. The resulting 2-aminomethyl-1,3-dienes could also be obtained via a one-pot three-component variant of this reaction involving aldehydes, amines, and organoindium reagents.