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Synfacts 2010(3): 0304-0304
DOI: 10.1055/s-0029-1219266
DOI: 10.1055/s-0029-1219266
Synthesis of Materials and Unnatural Products
© Georg Thieme Verlag
Stuttgart ˙ New York
Chiral Calixarenes
V. Gopalsamuthiram, A. V. Predeus, R. H. Huang, W. D. Wulff*
Michigan State University, East Lansing, USA
Weitere Informationen
Publikationsverlauf
Publikationsdatum:
18. Februar 2010 (online)

Significance
Optically active calix[4]arenes where the chirality comes from the substitution of the methylene bridges are presented for the first time. Usual strategies for the synthesis of optically active calixarenes come from substitution either on the benzene rings or on the alkoxy substituents. This family of molecules is relevant as scaffolds for chiral recognition events.