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Synlett 2019; 30(10): 1174-1177
DOI: 10.1055/s-0037-1611942
DOI: 10.1055/s-0037-1611942
cluster
Electrochemical Synthesis of 2-Hydroxy-para-terphenyls by Dehydrogenative Anodic C–C Cross-Coupling Reaction
S.R.W. thanks the DFG (Wa1276/14-1) for financial support. S.L. and S.R.W. acknowledge the Carl-Zeiss Foundation for granting a fellowship and the research network ELYSION, respectively.
Further Information
Publication History
Received: 14 November 2018
Accepted after revision: 04 December 2018
Publication Date:
08 January 2019 (online)
Published as part of the Cluster Electrochemical Synthesis and Catalysis
Abstract
The anodic C–C cross-coupling reaction provides fast access to a wide range of bi- and terarylic scaffolds by electrochemically mediated arylation reactions. Herein, a metal- and reagent-free electrosynthetic protocol for the synthesis of nonsymmetrical 2-hydroxy-para-teraryl derivatives is presented for the first time. It is scalable, easy to conduct, and allows the use of a broad variety of different functional groups.
Key words
C–C coupling - protecting groups - electrochemistry - C–H activation - arylation - terphenylsSupporting Information
- Supporting information for this article is available online at https://doi.org/10.1055/s-0037-1611942.
- Supporting Information
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References and Notes
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