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Synfacts 2006(4): 0307-0307  
DOI: 10.1055/s-2006-932026
Synthesis of Natural Products and Potential Drugs
© Georg Thieme Verlag Stuttgart · New York

Syntheses of Welwitindolinone A and Fischerindoles I

Contributor(s): Philip Kocienski, John Cooksey
P. S. Baran*, J. M. Richter
The Scripps Research Institute, La Jolla, USA
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Publikationsverlauf

Publikationsdatum:
24. März 2006 (online)

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Significance

Baran and Richter convert (S)-carvone oxide to Welwitindolinone A and Fischer­indoles I and G in seven and eight steps, respectively, without the use of a single protecting group. It is noteworthy that all the necessary carbon atoms of the target molecules were secured in only three steps.