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DOI: 10.1055/s-2008-1078442
Heteropoly Acid Catalyzed Hydroamination of Alkenes
Rezensent(en):Yasuhiro Uozumi, Yoichi M. A. Yamada, Chung Keun JinLanzhou Institute of Chemical Physics, P. R. of China and National University of Singapore, Singapore
Heteropoly Acids: A Green and Efficient Heterogeneous Brønsted Acidic Catalyst for the Intermolecular Hydroamination of Olefins
Tetrahedron Lett. 2008, 49: 2882-2885
Publikationsverlauf
Publikationsdatum:
20. Juni 2008 (online)
Key words
heteropoly acids - intermolecular hydroamination - amides - olefins
Significance
Heteropoly acids (HPAs) catalyzed hydroamination of alkenes was described. Thus, the intermolecular hydroamination of alkenes (2 mol equiv) with amides or carbamates was performed in the presence of H4SiW12O40nH2O (3 mol%) in dichloroethane (DCE) at r.t. to 85 °C to afford the corresponding products 1-14 in 48-91% isolated yield. The catalyst was reused twice with slight loss of catalytic activity (1st use = 78%, 2nd use = 74%, 3rd use = 62%).
Comment
H4SiW12O40nH2O was the most efficient HPAs catalyst (2: 95%) compared with H3PW12O40nH2O (2: 63%), H3PMo12O40nH2O (2: 82%), Na3PMo12O40 (no reaction), (NH4)3PW12O40 (2: trace) and Ag3PW12O40 (2: trace). The catalyst was recycled via simple filtration and washing with DCE.