DOI: 10.1055/s-00035024

Thrombosis and Haemostasis

Issue 02 · Volume 99 · 2008 DOI: 10.1055/s-007-35411

Editorial Focus

249
Semple, John W.: Platelets play a direct role in sepsis-associated endothelial cell death

Obituary

250
Augustin, Hellmut G.; Breier, Georg: Judah Folkman

Theme Issue Editorial

251
Preissner, Klaus T.: From Molecules to Medicine: New Horizons in Vascular Biology and Thrombosis

Theme Issue Article

253
Nurden, Paquita; Nurden, Alan T.: Congenital disorders associated with platelet dysfunctions
264
Bergmeier, Wolfgang; Chauhan, Anil K.; Wagner, Denisa D.: Glycoprotein Ibα and von Willebrand factor in primary platelet adhesion and thrombus formation: Lessons from mutant mice
271
Denis, Cécile V.; Christophe, Olivier D.; Oortwijn, Beatrijs D.; Lenting, Peter J.: Clearance of von Willebrand factor
279
Barberis, Laura; Hirsch, Emilio: Targeting phosphoinositide 3-kinase γ to fight inflammation and more
286
Kanse, Sandip M.; Parahuleva, Mariana; Muhl, Lars; Kemkes-Matthes, Bettina; Sedding, Daniel; Preissner, Klaus T.: Factor VII-activating protease (FSAP): Vascular functions and role in atherosclerosis
290
Christiaens, Valerie; Scroyen, Ilse; Lijnen, H. Roger: Role of proteolysis in development of murine adipose tissue
295
Hughes, Michael; Lip, Gregory Y. H.; on behalf of the Guideline Development Group for the NICE national clinical guideline for management of atrial fibrillation in primary and secondary care; on behalf of: Stroke and thromboembolism in atrial fibrillation: A systematic review of stroke risk factors, risk stratification schema and cost effectiveness data
Online Supplementary Material (PDF) Online Supplementary Material (PDF)

Review Article

305
Martorell, Lluis; Martínez-González, José; Rodríguez, Cristina; Gentile, Maurizio; Calvayrac, Olivier; Badimon, Lina: Thrombin and protease-activated receptors (PARs) in atherothrombosis

Blood Coagulation, Fibrinolysis and Cellular Haemostasis

316
Inomo, Akifumi; Sugi, Toshitaka; Fujita, Yoshimi; Matsubayashi, Hidehiko; Izumi, Shun-ichiro; Mikami, Mikio: The antigenic binding sites of autoantibodies to factor XII in patients with recurrent pregnancy losses
324
Zhang, Chuanling; Yu, Aiping; Yuan, Bin; Dong, Chunna; Yu, Hongyang; Wang, Lisheng; Wu, Chutse: Construction and functional evaluation of hirudin derivatives with low bleeding risk
331
Rosenkranz, Andrea; Hiden, Michael; Leschnik, Bettina; Eva-Christine, Weiss; Schlembach, Dietmar; Lang, Uwe; Gallistl, Siegfried; Muntean, Wolfgang: Calibrated automated thrombin generation in normal uncomplicated pregnancy
338
Adomaityte, Jurga; Farooq, Maria; Qayyum, Rehan: Effect of raloxifene therapy on venous thromboembolism in postmenopausal women: A meta-analysis
343
Meier, Thomas R.; Myers, Daniel D.; Wrobleski, Shirley K.; Zajkowski, Paul J.; Hawley, Angela E.; Bedard, Patricia W.; Ballard, Nicole E.; Londy, Frank J.; Kaila, Neelu; Vlasuk, George P.; Schaub, Robert G.; Wakefield, Thomas W.: Prophylactic P-selectin inhibition with PSI-421 promotes resolution of venous thrombosis without anticoagulation
352
Kinik, Sibel Tulgar; Özbek, Namik; Yuce, Muammer; Yazici, Ayse Canan; Verdi, Hasibe; Ataç, F. Belgin: PAI-1 gene 4G/5G polymorphism, cytokine levels and their relations with metabolic parameters in obese children

Platelets and Blood Cells

357
Neubauer, Horst; Lask, Sebastian; Engelhardt, Andreas; Mügge, Andreas: How to optimise clopidogrel therapy? Reducing the low-response incidence by aggregometry-guided therapy modification

Endothelium and Vascular Development

363
Kuckleburg, Christopher J.; Tiwari, Raksha; Czuprynski, Charles J.: Endothelial cell apoptosis induced by bacteria-activated platelets requires caspase-8 and -9 and generation of reactive oxygen species

Cardiovascular Biology and Cell Signalling

373
Dorweiler, Bernhard; Torzewski, Michael; Dahm, Manfred; Kirkpatrick, Charles James; Lackner, Karl J.; Vahl, Christian-Friedrich: Subendothelial infiltration of neutrophil granulocytes and liberation of matrix-destabilizing enzymes in an experimental model of human neo-intima
382
Orbe, Josune; Zudaire, Maite; Serrano, Rosario; Coma-Canella, Isabel; de Sizarrondo, Sara Martínez; Rodríguez, Jose A.; Páramo, Jose A.: Increased thrombin generation after acute versus chronic coronary disease as assessed by the thrombin generation test
388
Carty, Cara L.; Cushman, Mary; Jones, Daniel; Lange, Leslie A.; Hindorff, Lucia A.; Rice, Kenneth; Jenny, Nancy S.; Durda, J. Peter; Walston, Jeremy; Carlson, Christopher S.; Nickerson, Debbie; Tracy, Russell P.; Reiner, Alex P.: Associations between common fibrinogen gene polymorphisms and cardiovascular disease in older adults
Online Supplementary Material (PDF) Online Supplementary Material (PDF)

Cellular Proteolysis and Oncology

396
Stender, Mogens Tornby; Frøkjær, Jens Brøndum; Nielsen, Tina Sandie Hagedorn; Larsen, Torben Bjerregaard; Lundbye-Christensen, Søren; Elbrønd, Henrik; Thorlacius-Ussing, Ole: Combined use of clinical pre-test probability and D-dimer test in the diagnosis of preoperative deep venous thrombosis in colorectal cancer patients

Animal Models

401
Souri, Masayoshi; Koseki-Kuno, Shiori; Takeda, Naoki; Yamakawa, Mitsunori; Takeishi, Yasuchika; Degen, Jay L.; Ichinose, Akitada: Male-specific cardiac pathologies in mice lacking either the A or B subunit of factor XIII

New Technologies, Diagnostic Tools and Drugs

409
Jakubowski, Joseph A.; Payne, Christopher D.; Li, Ying G.; Brandt, John T.; Small, David S.; Farid, Nagy A.; Salazar, Daniel E.; Winters, Kenneth J.: The use of the VerifyNow P2Y12 point-of-care device to monitor platelet function across a range of P2Y12 inhibition levels following prasugrel and clopidogrel administration
416
Zürcher, Manuel; Sulzer, Irmela; Barizzi, Gabriela; Lämmle, Bernhard; Alberio, Lorenzo: Stability of coagulation assays performed in plasma from citrated whole blood transported at ambient temperature
Online Supplementary Material (PDF) Online Supplementary Material (PDF) Online Supplementary Material (PDF) Online Supplementary Material (PDF)
427
Raivio, Peter; Kuitunen, Anne; Petäjä, Jari; Ilveskero, Sorella; Lassila, Riitta: Monitoring high-dose heparinization during cardiopulmonary bypass – A comparison between prothrombinase-induced clotting time (PiCT) and two chromogenic anti-factor Xa activity assays
435
Tymvios, Charalambos; Jones, Sarah; Moore, Christopher; Pitchford, Simon C.; Page, Clive P.; Emerson, Michael: Real-time measurement of non-lethal platelet thromboembolic responses in the anaesthetized mouse

Case Report

441
De Paulis, Stefano; Rossi, Elena; Zamparelli, Roberto; Scapigliati, Andrea; Corrado, Michele; De Stefano, Valerio: Early postoperative obstructive prosthetic mitral valve thrombosis in a patient double heterozygous for factor V Leiden and prothrombin G20210A mutation
443
Barba, Pere; Santamaría, Amparo; Tirado, Isabel; Martí, Edelmira; Fontcuberta, Jordi: Antithrombin Cambridge II mutation as a risk factor to develop cerebral venous thrombosis
445
Jeanneret, Christina; Reutlinger, Christian; Hirsch, Hans H.; Cathomas, Gieri; Rothen, Madeleine; Martius, Ferdinand; Biedermann, Barbara C.: Multifocal thrombophlebitis and deep vein thrombosis in primary cytomegalovirus infection – A histopathological analysis

Letters to the Editor

448
Morel, Olivier; Bernhard, Nicolas; Desprez, Dominique; Grunebaum, Lelia; Freyssinet, Jean-Marie; Toti, Florence; Bareiss, Pierre: Residual prothrombotic status in low responder patients to clopidogrel identified by Vasodilator-Stimulated Phosphoprotein Phosphorylation (VASP) analysis?
451
Marchi, Rita; Carvajal, Zoila; Weisel, John W.: Comparison of the effect of different homocysteine concentrations on clot formation using human plasma and purified fibrinogen
453
Pecheniuk, Natalie M.; Elias, Darlene J.; Xu, Xiao; Griffin, John H.: Failure to validate association of gene polymorphisms in EPCR, PAR-1, FSAP and protein S Tokushima with venous thromboembolism among Californians of European ancestry