DOI: 10.1055/s-00035024

Thrombosis and Haemostasis

Issue 03 · Volume 93 · 2005 DOI: 10.1055/s-007-35804

Editorial Focus

399
Fleming, Ingrid: A spoonful of sugar helps the medicine go down… but platelet eNOS activity go up!
401
de Maat, Moniek P. M.: Genetic variation in the fibrinogen gene cluster

Review Article

403
Squizzato, Alessandro; Gerdes, Victor E. A.; Büller, Harry R.: Effects of human cytomegalovirus infection on the coagulation system

Rapid and Short Communication

411
Al-Shanqeeti, Ali; van Hylckama Vlieg, Astrid; Berntorp, Erik; Rosendaal, Frits R.; Broze, George J.: Protein Z and protein Z-dependent protease inhibitor

Blood Coagulation, Fibrinolysis and Cellular Haemostasis

414
Takamiya, Osamu; Kimura, Shinya: Molecular mechanism of dysfunctional factor VII associated with the homozygous missense mutation 331Gly to Ser
420
Minh Le, Thi Nguyet; Reza, Md Abu; Swarup, Sanjay; Kini, R. Manjunatha: Gene duplication of coagulation factor V and origin of venom prothrombin activator in Pseudonaja textilis snake
430
López, Mercedes; Mende, Katrin; Nowak, Goetz: Improvement of the specificity of dipetarudin by site directed mutagenesis
437
Peternel, Luka; Stegnar, Mojca; Drevenšek, Gorazd; Budihna, Metka V.; Božič, Mojca; Zega, Anamarija; Štalc, Anton; Černe, Manica; Urleb, Uroš: Antithrombotic potential of new direct thrombin inhibitors built on the azaphenylalanine scaffold in two rat venous thrombosis models
453
Scanavini, Daniela; Legnani, Cristina; Lunghi, Barbara; Mingozzi, Federico; Palareti, Gualtiero; Bernardi, Francesco: The factor VIII D1241E polymorphism is associated with decreased factor VIII activity and not with activated protein C resistance levels
457
Kreuz, Wolfhart; Gill, Joan C.; Rothschild, Chantal; Manco-Johnson, Marilyn J.; Lusher, Jeanne M.; Kellermann, Elke; Gorina, Eduard; Larson, Peter J.; and the International Kogenate-FS Study Group: Full-length sucrose-formulated recombinant factor VIII for treatment of previously untreated or minimally treated young children with severe haemophilia A
468
Tirado, Isabel; Mateo, José; Soria, José Manuel; Oliver, Arturo; Martínez-Sánchez, Elisabeth; Vallvé, Cristina; Borrell, Monserrat; Urrutia, Teresa; Fontcuberta, Jordi: The ABO blood group genotype and factor VIII levels as independent risk factors for venous thromboembolism
475
Dargaud, Yesim; Béguin, Suzette; Lienhart, Anne; Al Dieri, Raed; Trzeciak, Christine; Bordet, Jean Claude; Hemker, Coenraad H.; Negrier, Claude: Evaluation of thrombin generating capacity in plasma from patients with haemophilia A and B
481
Mariani, Guglielmo; Herrmann, Falko H.; Dolce, Alberto; Batorova, Angelika; Etro, Daniela; Peyvandi, Flora; Wulff, Karin; Schved, Jean F.; Auerswald, Günter; Ingerslev, Jorgen; Bernardi, Francesco; for the International Factor VII Deficiency Study Group (see appendix): Clinical phenotypes and factor VII genotype in congenital factor VII deficiency
488
Vormittag, Rainer; Vukovich, Thomas; Schönauer, Verena; Lehr, Stephan; Minar, Erich; Bialonczyk, Christine; Hirschl, Mirko; Pabinger, Ingrid: Basal high-sensitivity-C-reactive protein levels in patients with spontaneous venous thromboembolism
494
Kucher, Nils; Tapson, Victor F.; Goldhaber, Samuel Z.; for the DVT FREE Steering Committee: Risk factors associated with symptomatic pulmonary embolism in a large cohort of deep vein thrombosis patients
499
Kahn, Susan R.; Elman, Elyssa A.; Bornais, Chantal; Blostein, Mark; Wells, Phillip S.: Post-thrombotic syndrome, functional disability and quality of life after upper extremity deep venous thrombosis in adults
503
Blum, Alain; Bellou, Abdelouahab; Guillemin, Francis; Douek, Philippe; Laprévote-Heully, Marie-Claude; Wahl, Denis; and the GENEPI study group (see appendix): Performance of magnetic resonance angiography in suspected acute pulmonary embolism
512
Bonderman, Diana; Jakowitsch, Johannes; Adlbrecht, Christopher; Schemper, Michael; Kyrle, Paul A.; Schönauer, Verena; Exner, Markus; Klepetko, Walter; Kneussl, Meinhard P.; Maurer, Gerald; Lang, Irene: Medical conditions increasing the risk of chronic thromboembolic pulmonary hypertension

Blood Coagulation, Fibrinolysis and Cellular Haemostais

443
Ruiz-Torres, Maria Piedad; Casiraghi, Federica; Galbusera, Miriam; Macconi, Daniela; Gastoldi, Sara; Todeschini, Marta; Porrati, Francesca; Belotti, Daniela; Pogliani, Enrico Maria; Noris, Marina; Remuzzi, Giuseppe: Complement activation: the missing link between ADAMTS-13 deficiency and microvascular thrombosis of thrombotic microangiopathies

Platelets and Blood Cells

517
Massucco, Paola; Mattiello, Luigi; Russo, Isabella; Traversa, Monica; Doronzo, Gabriella; Anfossi, Giovanni; Trovati, Mariella: High glucose rapidly activates the nitric oxide/cyclic nucleotide pathway in human platelets via an osmotic mechanism
527
Zhao, Lian; Fletcher, Sally; Weaver, Chris; Leonardi-Bee, Jo; May, Jane; Fox, Sue; Willmot, Mark; Heptinstall, Stan; Bath, Philip: Effects of aspirin, clopidogrel and dipyridamole administered singly and in combination on platelet and leucocyte function in normal volunteers and patients with prior ischaemic stroke
535
Momi, Stefania; Pitchford, Simon C.; Alberti, Paolo F.; Minuz, Pietro; Del Soldato, Piero; Gresele, Paolo: Nitroaspirin plus clopidogrel versus aspirin plus clopidogrel against platelet thromboembolism and intimal thickening in mice
544
Schallmoser, Katharina; Rosin, Christiane; Knittelfelder, Regina; Sailer, Thomas; Ulrich, Silvia; Zoghlami, Claudia; Lehr, Stephan; Pabinger, Ingrid; Panzer, Simon: The FcγRIIa polymorphism R/H131, autoantibodies against the platelet receptors GPIbα and FcγRIIa and a risk for thromboembolism in lupus anticoagulant patients
549
Moffat, Karen A.; Ledford-Kraemer, Marlies R.; Nichols, William L.; Hayward, Catherine P. M.: Variability in clinical laboratory practice in testing for disorders of platelet function

Wound Healing and Inflammation/Infection

554
Reiter, Rosemarie A.; Varadi, Katalin; Turecek, Peter L.; Jilma, Bernd; Knöbl, Paul: Changes in ADAMTS13 (von-Willebrand-factor-cleaving protease) activity after induced release of von Willebrand factor during acute systemic inflammation
559
Silvestro, Antonio; Brevetti, Gregorio; Schiano, Vittorio; Scopacasa, Francesco; Chiariello, Massimo: Adhesion molecules and cardiovascular risk in peripheral arterial disease

Cell Signalling and Vessel Remodelling

564
Monraats, Pascalle S.; Rana, Jamal S.; Zwinderman, Aeilko H.; de Maat, Moniek P. M.; Kastelein, John P.; Agema, Willem R. P.; Doevendans, Pieter A. F.; de Winter, Robbert J.; Tio, René A.; Waltenberger, Johannes; Frants, Rune R.; van der Laarse, Arnoud; van der Wall, Ernst E.; Jukema, J. Wouter: –455 G/A polymorphism and preprocedural plasma levels of fibrinogen show no association with the risk of clinical restenosis in patients with coronary stent placement
570
Mannila, Maria Nastase; Eriksson, Per; Lundman, Pia; Samnegård, Ann; Boquist, Susanna; Ericsson, Carl-Göran; Tornvall, Per; Hamsten, Anders; Silveira, Angela: Contribution of haplotypes across the fibrinogen gene cluster to variation in risk of myocardial infarction
578
Blann, Andrew D.; Tan, Kiat T.; Tayebjee, Muzahir H.; Davagnanam, Indran; Moss, Mark; Lip, Gregory Y. H.: Soluble CD40L in peripheral artery disease

Cellular Proteloysis and Oncology

584
Vidal, Berta; Parra, Maribel; Jardí, Mercè; Saito, Shin'ichi; Appella, Ettore; Muñoz-Cánoves, Pura: The alkylating carcinogen N-methyl-N’-nitro-N-nitrosoguanidine activates the plasminogen activator inhibitor-1 gene through sequential phosphorylation of p53 by ATM and ATR kinases

Cellular Proteolysis and Oncology

592
Aujesky, Drahomir; Smith, Kenneth J.; Cornuz, Jacques; Roberts, Mark S.: Cost-effectiveness of low-molecular-weight heparin for secondary prophylaxis of cancer-related venous thromboembolism

New Technologies and Diagnostic Tools

600
Grand’Maison, Anne; Bates, Shannon M.; Johnston, Marilyn; McRae, Simon; Ginsberg, Jeffrey S.: "ProC Global": A functional screening test that predicts recurrent venous thromboembolism
605
Couturaud, Francis; Parent, Florence; Meyer, Guy; Girard, Philippe; Le Gal, Grégoire; Musset, Dominique; Simonneau, Gérald; Mottier, Dominique; Leroyer, Christophe: Effect of age on the performance of a diagnostic strategy based on clinical probability, spiral computed tomography and venous compression ultrasonography

Case Report

610
Schrijver, Iris; Hong, Debbie W.; Mandle, Lisa; Jones, Carol D.; Di Michele, Donna; Monahan, Paul E.; Zehnder, James L.: High frequency of premature termination mutations in the factorV gene: Three factorV deficiency case reports and a mutation review
612
Dear, Amy; Brennan, Stephen O.; George, Peter M.: Familial hypodysfibrinogenaemia associated with second occurrence of γ326 Cys→Tyr mutation

Letters to the Editor

614
Chen, Tsai-Yun; Lin, Tsun-Mei; Chen, Hsiao-Yen; Wu, Chiy-Lin; Tsao, Chao-Jung: Gly392Cys missense mutation in the A2 domain of factor V causing severe factor V deficiency: molecular characterization by expression of the recombinant protein
616
Patel, Raj K.; Ingram, Wendy; MacCarthy, Philip; Arya, Roopen: Is homozygosity for factor V Leiden a risk factor for myocardial infarction in young women who smoke?
618
Fimognari, Filippo L.; Piccirillo, Gianfranco; Lama, Jaime; Marzio, Paolo De; Morelli, Sergio; Monteleone, Girolamo; Mollace, Vincenzo; Violi, Francesco: Nocturnal rise of urinary thromboxane B2 in patients with coronary artery disease
620
Post, Marinka S.; Leurs, Judith R.; der Mooren, Marius J. van; Marchien van Baal, W.; Hendriks, Dirk F.; Stehouwer, Coen D.A.; Kenemans, Peter: Different effects of low-dose transdermal and oral oestrogen therapy on procarboxypeptidase U, an inhibitor of fibrinolysis, in healthy postmenopausal women: A randomised, placebo-controlled study
622
Craig, Steven; Leeming, David; Sidebotham, Allan; Stevenson, Ken: Rebuttal: A problem of calibration in the paper ‘Point of care monitoring of oral anticoagulant therapy in children’
623
Monagle, Paul: Reply to rebuttal: A problem of calibration in the paper ‘Point of care monitoring of oral anticoagulant therapy in children’