DOI: 10.1055/s-00000131

Synfacts

Issue 12 · Volume 14 · December 2018 DOI: 10.1055/s-008-41882

Synform

A186
Zanda, Matteo: SYNFORM ISSUE 2018/12

Synthesis of Natural Products and Potential Drugs

z1215
All PDFs of this category
1215
Synthesis of BMS-932481
1216
Synthesis of Tesirine
1217
Divergent Route to Gelsedine-Type Alkaloids
1218
Total Syntheses of Bisdehydroneostemoninine and Bisdehydrostemoninine
1219
Total Synthesis of Aspochalasan Natural Products
1220
Synthesis of (–)-Shishijimicin A
1221
Asymmetric Synthesis of Efinaconazole and Albaconazole
1222
Synthesis of a Ghrelin Receptor Agonist
1223
Total Synthesis of (–)-Alstoscholarisine A
1224
Synthesis of (–)-Nodulisporic Acid C
1225
Synthesis of (+)-Piericidin A
1226
Synthesis of GDC-0810
1227
Synthesis of Lorlatinib

Synthesis of Heterocycles

z1229
All PDFs of this category
1229
Stereoselective Synthesis of Phosphorothioate Nucleotides
1230
Chan–Lam Coupling/Friedel–Crafts Reaction Sequence to Acridines
1231
Reductive Isoxazoline-to-Pyrrolidone Ring Interconversion
1232
Rhodium(III)-Catalyzed Synthesis of 1,4-Dihydroisoquinolin-3(2H)-ones
1233
1-Phenylsulfonyl-3-Oxabicyclo[3.1.0]hexan-2-one for the Synthesis of Spirocycles
1234
Organocatalytic Route to Tetrahydrochromeno[4,3-b]pyrrol-4(1H)-ones
1235
Ru-Catalyzed Synthesis of Pyrazines and Pyrroles from Ammonia and Diols
1236
Synthesis of Indoloquinolines by a Dinitrogen-Extrusion/Cyclization Method
1237
Electrochemical Coupling of Benzothiophenes with Phenols
1238
Modified Paal–Knorr Cyclization Route to Substituted Pyrrolodiazepinones
1239
Enantioselective Synthesis of Pyrimidinones by the Biginelli Reaction
1240
Diastereoselective Cyclopropanation of Unsaturated Pyrazolones
1241
Palladium-Catalyzed Synthesis of Indolo[3,2-a]Carbazoles from Indoles
1242
Iron(III)-Catalyzed Asymmetric Synthesis of Tetrahydroindolizines

Synthesis of Materials and Unnatural Products

z1243
All PDFs of this category
1243
Rare Fluorescence Observed from Indacenes
1244
A More Tolerant Initiator for Living Aryl Isocyanide Polymerization
1245
New Photoactivatable Hydride Donors: Benzothiazole-Containing Terarylenes
1246
2D Heteroacenes: New Building Blocks for Organic Materials
1247
Mild, One-Pot Balz–Schiemann Reaction Accessible via Organotrifluoroborates
1248
Indoloindoles through Gold(I)/Rhodium(II) Catalyzed Cascade Cyclizations
1249
Butterfly in a Flask: Irregular Nanographenes by Highly Regioselective Domino Benzannulation
1250
Corannulenes with B–N Units on its Spoke
1251
A Thiophene, Pyrrole, and Furan Walk Into a Bar…
1252
Serendipitous Synthesis of Expanded Porphyrinoids
1253
Fluorinated Cycloparaphenylene: The Same and Not the Same
1254
Tunable Red-Emitting Bismuth-Containing Polymers in the Presence of Oxygen

Metal-Catalyzed Asymmetric Synthesis and Stereoselective Reactions

z1255
All PDFs of this category
1255
Nickel-Catalyzed Enantioselective Reductive Diarylation
1256
Palladium-Catalyzed Atroposelective C–H Activation
1257
Nickel-Catalyzed Enantioselective Hydroalkylation of 1,3-Dienes
1258
Palladium-Catalyzed Enantioselective Decarboxylative Allylic Alkylation
1259
Asymmetric Synthesis of 3-Allyl-3-hydroxyoxindoles
1260
Asymmetric Allylic Alkylation through Palladium and Copper Dual Catalysis
1261
Nickel–Catalyzed Diarylation of 1,2-Disubstituted Alkenylarenes
1262
Asymmetric Propargylation of 5H-Thia(oxa)zol-4-ones
1263
Rhodium-Catalyst Generates Cyclic Peptide Stereocenters in Sequence
1264
Palladium-Catalyzed Enantioselective Suzuki–Miyaura Coupling
1265
Copper-Catalyzed Stereoselective Hydrohalogenation of Internal Alkynes
1266
Enantioselective Aldol Reaction of Silyl Ketene Imines
1267
Palladium-Catalyzed Enantioselective Synthesis of 1H-Isoindoles
1268
Ruthenium-Catalyzed Transfer Hydrogenation of Axial Biaryl Imines via a DKR strategy
1269
Stereoselective Iridium–Catalyzed Haloamidation of Alkynes
1270
Diastereoselective Gold-Catalyzed Cyclization of Nitrones
1271
Ligand-Directed Gold-Catalyzed Annulations of Ynamides and 1,2-Benzisoxazoles
1272
Palladium-Catalyzed Enantioselective C–H Olefination of Oxime Ethers
1273
Enantioselective 3-Alkylation of Benzofuranones with α-Diazo Esters
1274
Copper-Catalyzed Synthesis of Atropisomeric 2′-Iodo[1,1′-biphenyl]-2-yl Thioates
1275
Ru-Catalyzed Asymmetric Transfer Hydrogenation of Dihalo Keto Esters or Amides
1276
Enantioselective [4+1] Cycloaddition of Danishefsky’s Diene and Diazoarylacetates
1277
New Ligands for the Iridium-Catalyzed Asymmetric Hydrogenation of Olefins
1278
Palladium-Catalyzed Carboannulation for Chiral Indane Synthesis
1279
Application of Novel N-Tosyl Bisimidazoline Ligands in Palladium(II)-Catalyzed Arylation
1280
Gold-Catalyzed Enantioselective Synthesis of Indolyl Cyclopenta[c]furans
1281
Nickel-Catalyzed Carboiodination
1282
Spiroketal Bisphosphine Rhodium Complexes for Asymmetric Hydrogenation

Metal-Mediated Synthesis

z1283
All PDFs of this category
1283
para-Ketonization Using Electrophilic Vinyl Ethers
1284
Transition-Metal-Free Synthesis of Chiral Aniline Derivatives
1285
Carbozincation of Alkynes Catalyzed by Rhodium Complexes
1286
Bimetal-Catalyzed Benzylic Arylation of Toluenes
1287
Asymmetric Synthesis of C,C-Diaryl Hydantoins
1288
Nickel-Catalyzed α-Alkylation of Ketones with Alcohols
1289
C–F Bond Functionalization via a Nickel-Catalyzed Cross-Coupling
1290
A New Isocyanide Functionalization
1291
A New Di-trifluoromethylation of Arynes
1292
Chiral Diamine Enantioselective Addition of Me2Zn to Fluorinated Ketones
1293
Diastereoselective Copper-Catalyzed Synthesis of Unsaturated Trialkylsilyl Esters
1294
Palladium(I)-Catalyzed Oxidative Cross-Coupling
1295
Copper-Mediated Direct C–H Difluoromethylation of Heteroarenes

Organo- and Biocatalysis

z1297
All PDFs of this category
1297
Asymmetric Phosphoric Acid Catalyzed Four-Component Ugi Reaction
1298
Photoredox-Catalyzed Decarboxylative Radical Cyclization Cascade
1299
Asymmetric Organocatalytic Vicinal Difluorination of Styrenes
1300
Asymmetric Enzymatic Hydration of Nonactivated Olefins
1301
Asymmetric Oxidative Coupling of Carboxylic Acids to α-Branched Aldehydes
1302
Synthesis of Axially Chiral Anilides by Atroposelective Allylic Alkylation
1303
N-Heterocyclic Carbene Catalyzed Umpolung Acylation in Fullerene Chemistry
1304
Functionalization of Enamides Catalyzed by a Chiral Phosphoric Acid
1305
Application of Nitrones for the Asymmetric Synthesis of Substituted Piperidines

Polymer-Supported Synthesis

z1307
All PDFs of this category
1307
Palladium Nanoparticle Catalyzed Cyanation of Iodobenzenes
1308
Huisgen Reaction Catalyzed by Silica-Coated Magnetic Copper Nanoparticles
1309
Alkyne–Azide Cycloaddition on Water-Soluble Copper NP–Cobaltocene Catalyst
1310
Three-Component Reactions in Water with a Supported Cu(I) Acetylacetonate Composite
1311
Oxidative C=C Cleavage of Styrenes with Supported Cobalt Vanadium Oxide
1312
Photooxidative Coupling of Amines Catalyzed by Mixed-Phase 2D-Molybdenum Sulfide
1313
Oxidative Esterification with N-Doped Carbon-Incarcerated Co/Cu Nanoparticles
1314
Transfer Hydrogenation with Formic Acid Catalyzed by Cobalt on Mesoporous Carbon
1315
Ruthenium-Catalyzed Carbonylative Synthesis of Quinazolinones
1316
Oxidative Coupling of Phenylglyoxals with Amines on Gold Nanoparticles in Water
1317
Aerobic Oxidation of Alcohols with a Heterogeneous Iodine Catalyst
1318
Petasis Reaction on Reduced Graphene Oxide Supported CuO Nanoparticles
1319
Halogenation of Anilides and Quinolines on a MnO-Supported Copper Catalyst

Flow Chemistry

z1321
All PDFs of this category
1321
Synthesis of N-Carboxyanhydrides in a Microflow Reactor
1322
Combined Photoredox/Hydrogen Transfer for Functionalization of Nonactivated Alkanes
1323
Iron-Catalyzed Arylhydroxylation in Continuous Flow
1324
Light Absorption of a Palladium–Zinc Complex allows Negishi Cross-Couplings
1325
Enantioselective Synthesis of Quaternary α-Amino Acids in Flow
1326
Flow Synthesis of a Doravirine Fragment