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Synfacts 2008(12): 1305-1305  
DOI: 10.1055/s-0028-1083617
Metal-Catalyzed Asymmetric Synthesis and Stereoselective Reactions
© Georg Thieme Verlag Stuttgart ˙ New York

Hydrogenation of Ketones to Provide Aryl Allylic Alcohols

Contributor(s): Hisashi Yamamoto, Joshua P. Abell
N. Arai, K. Azuma, N. Nii, T. Okhuma*
Hokkaido University, Sapporo, Japan
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Publication History

Publication Date:
20 November 2008 (online)

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Significance

Although asymmetric hydrogenation of prochiral ketones has been well established, the reduction of α,β-unsaturated aryl ketones is still challenging due to the discrimination between two sp² functionalities of the ketone.