Asymmetric Hydrogenation of Heteroaromatics Using Brønsted and Lewis Acid Substrate Activation

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Synfacts 2024; 20(07): 0679
DOI: 10.1055/s-0043-1773314

Synthesis of Heterocycles

Contributor(s):

Paul Richardson (Pfizer)

BTK inhibitors - zanubrutinib - iridium catalysis - asymmetric hydrogenation - substrate activation - Brønsted acids - Lewis acids

Article published online:
14 June 2024

Georg Thieme Verlag KG
Rüdigerstraße 14, 70469 Stuttgart, Germany