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Synfacts 2006(2): 0116-0116  
DOI: 10.1055/s-2005-924831
Synthesis of Heterocycles
© Georg Thieme Verlag Stuttgart · New York

A C-H Insertion Route to Fused Indoles

Contributor(s): Victor Snieckus, Till Vogel
C. Bressy, D. Alberico, M. Lautens*
University of Toronto, Canada
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Publikationsdatum:
23. Januar 2006 (online)

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Significance

A Pd-catalyzed, mechanistically complex, tandem cross-coupling reaction sequence for the synthesis of annulated indoles in moderate to good yields is reported. A variety of electron-donating and -withdrawing substituents tolerate the conversion.