DOI: 10.1055/s-00000017

Experimental and Clinical Endocrinology & Diabetes

Ausgabe S 04 · Volume 104 · 1996 DOI: 10.1055/s-002-19243

Session 1: Molecular pathogenesis of thyroid tumors

1
Farid, N. R.: Molecular pathogenesis of thyroid cancer: the significance of oncogenes, tumor suppressor genes, and genomic instability
13
Simon, D.; Köhrle, J.; Schmutzler, C.; Mainz, K.; Reiners, C.; Röher, H.-D.: Redifferentiation therapy of differentiated thyroid carcinoma with retinoic acid: basics and first clinical results
16
Schmutzler, C.; Brtko, J.; Bienert, K.; Köhrle, J.: Effects of retinoids and role of retinoic acid receptors in human thyroid carcinomas and cell lines derived therefrom
20
Bröcker, M.; de Buhr, I.; Papageorgiou, G.; Schatz, H.; Derwahl, M.: Expression of apoptosis-related proteins in thyroid tumors and thyroid carcinoma cell lines
24
Pötter, E.; Schoenermark, M.; Böck, O.; Hoang-Vu, C.; Munari-Silem, Y.; Rousset, B.; Brabant, G.: Cell adhesion receptors and gap junctions in normal and neoplastic transformed thyrocytes
29
Hoelting, Th.; Duh, Q.-Y.; Clark, O. H.; Herfarth, Ch.: The regulation of proliferation and invasion in differentiated thyroid cancer by growth factors

Session 2: Molecular pathogenesis of nodular goiter

32
Derwahl, Michael: Molecular aspects of the pathogenesis of nodular goiters, thyroid nodules and adenomas
36
Gärtner, R.; Veitenhansl, M.; Aktas, J.; Schopohl, D.: Role of basic fibroblast growth factor in the pathogenesis of nodular goiter
39
Poertl, S.; Kirner, J.; Mann, K.; Hoermann, R.: Enhanced functional activity in thyroid adenomas in vitro
41
Dugrillon, A.: Iodolactones and iodoaldehydes — mediators of iodine in thyroid autoregulation

Session 3: Molecular aspects of autoimmune disease

46
Nakashima, M.; Kong, Y. M.; Wan, Q.; Davies, T. F.: Prospective study of T cell receptor utilization following the induction of murine thyroiditis*
52
Hunt, Nicholas; Ruppert, Jorg; Willey, Kevan; Schulte, Heinrich M.: Epitope mapping of the human TSH receptor; Structure function studies
56
Morgenthaler, N. G.; Scherbaum, W. A.; Banga, J. P.: In vitro synthesized TSH receptor as a tool for autoantibody detection
60
Schumm-Draeger, Petra-Maria; Jungheim, K.; Caspar, G.; Hermann, G.; Fortmeyer, H. P.; Wenisch, H. J. C.; Usadel1, K. H.: Effect of Graves’ intrathyroidal lymphocytes
64
Aust, G.; Scherbaum, W. A.: Expression of cytokines in the thyroid: thyrocytes as potential cytokine producers
68
Schuppert, Frank; Hiller, Wolfgang; Weinland, Günter; Hoang-Vu, Cuong; Mühlen, Alexander von zur; Kohn, Leonard D.: Iodide, cytokines and TSH-receptor expression in Graves' disease
75
Wenzel, Björn E.; Peters, Achim; Zubaschev, Igor: Bacterial virulence antigens and the pathogenesis of autoimmune thyroid diseases (AITD)
79
Kahaly, G.; Otto, E.; Förster, G.; Gansen, K.; Olivari, N.; Beyer, J.; Hansen, Ch.: T cells and orbital connective tissue in endocrine orbitopathy
84
Heufelder, A. E.; Schworm, H.-D.; Wenzel, B. E.; Garrity, J. A.; Bahn, Rebecca S.: Molecular analysis of antigen receptor variable region repertoires in T lymphocytes infiltrating the intrathyroidal and extrathyroidal manifestations in patients with Graves' disease*
88
Hoermann, R.: Stimulation of thyroidal and extrathyroidal thyrotropin receptors

Session 4: Molecular diagnostics of thyroid diseases and diseases of the parathyroid glands

92
Finke, R.: Theoretical basis and application of molecular diagnostics
98
Badenhoop, K.; Donner, H.; Braun, J.; Siegmund, T.; Rau, H.; Usadel, K. H.: Genetic markers in diagnosis and prediction of relapse in Graves’ disease*
101
Schulte, Klaus-Martin; Niederacher, Dieter; An, Han-Xiang; Staudt, Stephanie; Simon, Dietmar; Beckmann, Matthias Wilhelm; Goretzki, Peter E.: INT-2 gene amplification in differentiated human thyroid cancer
105
Dotzenrath, Cornelia; Goretzki, P. E.; Farnebo, F.; Teh, B. T.; Weber, G.; Röher, H. D.; Larsson, Catharina: Molecular genetics of primary and secondary hyperparathyroidism
108
Frank-Raue, K.; Höppner, W.; Buhr, H.; Herfarth, Ch.; Ziegler, R.; Raue, F.: Application of genetic screening in families with hereditary medullary thyroid carcinoma*
111
Behr, Michael; Loos, Ulrich: Periodically hyperthyroid phenotype in thyroid hormone resistance is associated with mutation D322N in the thyroid hormone receptor ß gene: Transcriptional properties of the mutant and the role of retinoid X receptor
117
Krude, H.; Biebermann, H.; Göpel, W.; Grüters, A.: The gene for the thyrotropin receptor (TSHR) as a candidate gene for congenital hypothyroidism with thyroid dysgenesis
121
Grüters, A.; Köhler, B.; Wolf, A.; Söling, A.; Vijlder, L. de; Krude, H.; Biebermann, H.: Screening for mutations of the human thyroid peroxidase gene in patients with congenital hypothyroidism
124
Schwab, K. O.; Söhlemann, P.; Gerlich, M.; Broecker, M.; Petrykowski, W. v.; Holzapfel, H. P.; Paschke, R.; Grüters, A.; Derwahl, M.: Mutations of the TSH receptor as cause of congenital hyperthyroidism*
129
Paschke, R.: Constitutively activating TSH receptor mutations as the cause of toxic thyroid adenoma, multinodular toxic goiter and autosomal dominant non autoimmune hyperthyroidism